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Primary cicatricial alopecia, a rare disorder causing permanent hair loss, is hard to diagnose and treat, with treatments like anti-inflammatory drugs and steroids offering varied results and no guaranteed cure. Psychological support for patients is important, and future research should aim to identify causes of the condition.

A specific gene variant causes severe skin issues and increases infection risk, requiring careful medical monitoring.

The document concludes that more research is needed to find effective treatments for Lichen planopilaris and Frontal fibrosing alopecia.

The conclusion is that early diagnosis of skin signs linked to diseases like Lupus, Dermatomyositis, and Rheumatoid Arthritis is crucial to prevent serious complications.

Frontal fibrosing alopecia is a poorly understood condition with increasing cases and unclear treatment effectiveness.

Antigen presenting cells around hair follicles are crucial in SLE-related hair loss.

A man developed autoimmune issues after a transplant, improved with treatment, but died from leukemia relapse.

Early treatment of Lupus Erythematosus Alopecia can prevent permanent hair loss, and various medications are effective.

Transverse scalp biopsy sections help diagnose different alopecias by showing hair follicle details and inflammation patterns.

A patient with pemphigus vulgaris improved significantly after treatment for an additional viral skin infection.

The main difference in hair loss for lupus patients is smaller and fewer sebaceous glands.

A man wrongly believed he had parasites, showing that delusional infestation can affect men and is often linked with other psychiatric issues, but can be treated with antipsychotics.

The review suggests more research is needed to understand Frontal fibrosing alopecia, a condition causing hairline recession in postmenopausal women.

The document says doctors should identify and treat Frontal fibrosing alopecia medically before considering surgery, as treatments often don't work well.

A woman was diagnosed with porphyria cutanea tarda and improved with phlebotomy and lifestyle changes.

Scarring alopecia, a type of hair loss, is most common in females under 35, often caused by discoid lupus erythematosus and pseudopelade of Brocq. Skin punch biopsy and histopathology are key to identifying its cause.

Besnoitiosis, a parasitic disease, has been found in donkeys in Italy and may be more common in Europe than previously thought.

Mycophenolate mofetil helped reduce steroid use in treating a dog's autoimmune skin disease.

The Bcl-2 protein is important for keeping hair follicle stem cells working and preventing hair loss.

Toxic Epidermal Necrolysis is a rare, serious skin condition that can affect anyone, is more common in women, and may be linked to genetics, with a 20% mortality rate mainly due to sepsis.

Recombinant cytokine therapy can cause skin reactions ranging from mild to severe.

Hair can regrow after certain stem cells are lost because other stem cells can take over their role.

Blocking TSLP reduces skin inflammation and cell overgrowth in psoriasis.

The cause of alopecia areata is likely a mix of genetics, immune system issues, and environmental factors, with more research needed to understand it fully.

Plasmalogens activate a channel in cells that may stimulate hair growth.

The document concludes that permanent hair loss conditions are complex, require early specific treatments, and "secondary permanent alopecias" might be a more accurate term than "secondary cicatricial alopecia."

Herpes simplex virus infections should be considered in pemphigus patients to avoid unnecessary changes in treatment.

Modern skin cancer treatments can cause skin side effects and hair loss, affecting patients' quality of life.

Implanting hair-follicle stem cells in mice brains helped repair brain bleeding and reduced brain inflammation.

Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, and antioxidants may help treat hair loss.