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This study found that Diane®, a combination of cyproterone acetate and ethinyl estradiol, is an effective contraceptive and treatment for acne and seborrhea, but less effective for pronounced hair growth.

This review discusses the preclinical findings on cyproterone acetate and suggests that while it has a low potential cancer risk for patients, its tumor effects in female rats may involve both genotoxic and mitogenic mechanisms.

In this study, ethyl acetate fraction of Eclipta alba was found to inhibit adipogenesis and reduce dyslipidemia in hamsters, suggesting potential as an herbal treatment for obesity.

The researchers reported that nicotinic acid normalized excessive sebaceous lipogenesis without affecting basal lipogenesis and suggested potential anti-acne benefits.

This study found that ACOD1 deficiency in dermal papilla cells promotes mitochondrial dysfunction and contributes to cellular senescence in androgenetic alopecia, suggesting ACOD1 as a potential therapeutic target and 4-octyl itaconate as a promising treatment option for AGA.

In this study, researchers synthesized the fictional compound 1-hydroxyindole and discovered its potential medical applications, including anti-aging properties, itch relief for atopic dermatitis, and as a stronger treatment for dementia compared to cilostazol. Additionally, they found that 1-methoxyindole derivatives function as anticancer agents in diets.

This article discusses the functions of the enzyme 17beta-HSD10, including its role in steroid metabolism and potential links to Alzheimer's disease, but reports no new experimental findings.

Diphencyprone initially increases mouse hair growth, then slows it, possibly due to changes in specific protein levels.

This article reviews the use of anti-androgens, particularly cyproterone acetate, for managing hirsutism, but does not provide new clinical results.

This study found that the enzyme encoded by Dgat1 acts as a retinol acyltransferase in murine epidermis, protecting against retinoid toxicity and alopecia by preventing retinol accumulation.

This study found that dimethylarsinic acid significantly accelerates skin tumor development in hair follicle-targeted K6/ODC transgenic mice.

In this study, beagle dogs treated with hydrocortisone 17-butyrate 21-propionate ointment showed various toxic effects, including acne-like skin changes and organ atrophy, which returned to normal after a recovery period.

This source reports that clascoterone cream has been approved in the U.S. for treating acne vulgaris in patients aged 12 and older, suggesting it works by competing with dihydrotestosterone at androgen receptors to mitigate acne's effects.

This study found that using a bicomponent reduction system with TGA and DTDG for hair straightening limited hair damage by forming only thiol groups, while a TGA-only system formed more damaging mixed disulfide groups.

In this study, the n-hexane fraction of Carthamus oxyacantha methanolic extract exhibited significant 5α-reductase inhibitory activity in vitro, suggesting potential therapeutic use for benign prostatic hyperplasia through DHT inhibition.

This case report describes an 18-year-old male whose acne, unresponsive to traditional treatments and only partially improved with oral isotretinoin, was linked to androgen metabolism anomalies indicative of a non-classical form of congenital adrenal hyperplasia.

This study observed that insulin-dependent diabetes induces specific molecular changes in the keratin structure of hair, potentially offering a new way to study diabetic complications through easily accessible tissues.

This study concluded that intramuscular administration of medium-dose cyproterone acetate with oral ethinylestradiol is highly effective in managing hirsutism, showing better response rates than high-dose oral treatment.

In this study, cyproterone acetate combined with estradiol dramatically improved hirsutism symptoms and significantly reduced plasma testosterone and androstenedione levels in patients over periods of up to three years.

This study identified several active compounds in Houttuynia cordata and found that most demonstrated significant antioxidant and acetylcholinesterase inhibitory activity, potentially useful for developing functional tea products.

This paper describes a new scalable synthesis method for Dutasteride, highlighting its potential for large-scale commercial production.

The authors reported that 4-O-methylhonokiol decreased TGF-β1-induced cell cycle arrest and oxidative stress markers in human keratinocyte cells, suggesting a potential protective role in TGF-β1-mediated cell cycle regulation.

This study identified that the biosynthetic pathways for coumestans in Eclipta prostrata are derived from acetate and shikimate pathways, while phenylpropanoid biosynthesis is exclusively from the shikimate pathway.

This study found that ethyl acetate extract from mangosteen pericarp exhibited the strongest antibacterial effect against Propionibacterium acnes compared to other extraction solvents.

In this study, Diane was reported to effectively treat acne, seborrhoea, androgenic alopecia, and mild hirsutism in hirsute women, with its effectiveness influenced by the severity and duration of the condition.

This study aimed to assess how hydroquinone-based body milks affect blood glucose levels in diabetic women in Senegal but does not provide new results.

This study reports that injecting a non-cross-linked hyaluronic acid compound into keratosis pilaris-affected skin led to significant improvements in roughness, redness, and overall skin condition, while maintaining a favorable safety profile, making it a promising alternative treatment option.