The Treatment of Androgenized Women with Intramuscularly Administered Cyproterone Acetate

    May 1983 in “ Geburtshilfe und Frauenheilkunde ”
    L. Moltz, F. Haase, U. Schwartz, J. Hammerstein
    TLDR Intramuscular cyproterone acetate effectively treats hirsutism and improves skin conditions in women with hyperandrogenism.
    The study evaluated the effectiveness of intramuscular cyproterone acetate (CPA) in treating hyperandrogenism in 42 women, with a total of 293 treatment cycles. Patients received 300 mg of CPA monthly, followed by 40 μg of oral ethinylestradiol for 21 days. The treatment was applied as primary therapy and as a follow-up for those who failed low-dose and high-dose oral CPA therapies. Results showed satisfactory to good responses in hirsutism: 83.5% in primary therapy, 100% in low-dose failures, and 57% in high-dose failures. Seborrhea improved in 100% of primary and low-dose groups and 89% in the high-dose group, while acne and androgenetic alopecia improved in all groups. Side effects were similar to those of high-dose oral CPA, leading to treatment discontinuation in only 3 cases. Although the pharmacokinetics study did not clarify the clinical superiority of parenteral CPA, the findings suggested it was an effective treatment for hirsutism.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 107 results

      community Ru58841 for a female w male pattern baldness

      in General  166 upvotes 1 year ago
      A user is considering using RU58841 for female pattern baldness and is also planning to use Minoxidil. They are hesitant to ask their doctor for spironolactone due to its cosmetic nature and are experiencing significant hair loss possibly due to stress and hormonal issues.

      community Doctors won't let me try bicalutamide or fin

      in Female  7 upvotes 4 years ago
      Hair loss treatments discussed include 200mg Spiro, bicalutamide, and finasteride. Endocrinologist advises against bicalutamide and finasteride due to potency and risks.

      community Spironolactone for hair loss??

      in Product  6 upvotes 3 years ago
      Hair loss treatments discussed include Minoxidil, Finasteride, and Spironolactone. One user shares success with Finasteride, Minoxidil, and low-dose Cyproterone Acetate, but warns against long-term use of oral anti-androgens.

      community Extreme regimen and still miniaturized hairs. AGA is just impossible to beat.

      in Insane  31 upvotes 3 years ago
      A user's extreme regimen for hair loss, which includes taking oral and topical medications such as minoxidil, dutasteride, cyproterone acetate and bicalutamide, but still experiencing miniaturization. Suggestions were made to try other treatments such as RU58841 and Pyrilutamide, while also considering mental health treatment and advice on lookmaxxing.

      community 5 months of nuking T, 2 months of minoxidil

      in Transgender  487 upvotes 1 year ago
      The user transitioned from finasteride to Cyproterone and started using Minoxidil, resulting in healthier hair and regrowth. They plan to wean off Minoxidil in a year, depending on regrowth.

    Similar Research

    6 / 1000+ results