Study on Toxicity of Hydrocortisone 17-Butyrate 21-Propionate: Subacute Toxicity in Dogs by Percutaneous Administration

January 1981 in “ The Journal of Toxicological Sciences ”

Yasuo Tarumoto, Takashi Sakagawa, Yoshifumi TSUTSUI … Masahiro OHZEKI

hydrocortisone 17-butyrate 21-propionate HBP acne-like changes inhibited hair growth lymphocytes eosinophils cholesterol triglycerides thymus adrenal weight loss gastric mucosa hemorrhage atrophy hepatocyte enlargement hydrocortisone acne hair growth inhibition white blood cells fat in blood stomach lining bleeding tissue shrinkage liver cell enlargement

Studysummary In this study, beagle dogs treated with hydrocortisone 17-butyrate 21-propionate ointment showed various toxic effects, including acne-like skin changes and organ atrophy, which returned to normal after a recovery period.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer ·

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