This study found that the optimized AR antagonist compound 39 showed potent hair growth activity with improved safety in mice, suggesting potential for better topical treatments for androgenetic alopecia.
In a mouse hair-growth model, this study found that the optimized compound 39 matched the efficacy of pyrilutamide for androgenic alopecia, with faster response and maintained safety, suggesting it as a promising topical AR antagonist with reduced systemic toxicity risk.
In this study, a dual soft drug design strategy improved the AR antagonist candidate 39, showing potent AR antagonism and good safety in a mouse hair-growth model, with similar efficacy to pyrilutamide but faster response.
This study found that the optimized AR antagonist candidate 39, in a hair-growth mouse model, achieved similar efficacy to pyrilutamide with faster onset and favorable safety, suggesting a promising approach for developing topical treatments with low systemic toxicity for androgenetic alopecia.
This study reports that the newly optimized AR antagonist 39 demonstrated effective hair growth and safety in a mouse model of androgenetic alopecia, showing comparable efficacy to pyrilutamide with faster response and favorable pharmacokinetics, due to innovative structural design and dual metabolic inactivation strategy.
July 2026 in “Journal of Medicinal Chemistry” In this study, candidate compound 39 demonstrated potent androgen receptor antagonism and faster hair-growth efficacy in a mouse model compared to pyrilutamide, while maintaining favorable safety and pharmacokinetic profiles, suggesting potential for topical use in androgenic alopecia.
June 2026 in “International Journal of Scientific Engineering and Technological Research and Innovations” This review highlights the potential of nanoparticle-based shampoos to improve dandruff treatment and cosmetic performance while noting concerns about nanoparticle toxicity and environmental safety that require further investigation.
June 2026 in “Actas Dermo-Sifiliográficas” This review describes the technique of follicular unit extraction with long hair, which allows for hair transplantation in androgenetic alopecia patients without shaving the donor area, and outlines its benefits, drawbacks, and primary use cases.
This scoping review aims to consolidate evidence on the experiences of cancer patients undergoing chemotherapy in oncology facilities across sub-Saharan Africa, highlighting common physical, psychological, and social challenges and identifying under-researched areas for future study.
March 2026 in “Journal of Medicinal Plants Studies” This source reviews the traditional and contemporary medicinal uses of Murraya koenigii, reporting its significant pharmacological activities, including antioxidant and anticancer effects, supported by both preclinical and clinical research.
January 2026 in “International journal of research and scientific innovation” In this laboratory study, researchers developed a multifunctional organic hair cream with various natural extracts, finding that the cream with 15% extracts demonstrated higher physical stability, hair strength, and antimicrobial activity compared to lower concentration samples and synthetic alternatives.
October 2025 in “Burns & Trauma” This review highlights recent advancements in engineered probiotics for wound healing, reporting that genetically engineered strains of Lactobacillus reuteri and Lactococcus cremoris have shown promise in promoting faster wound healing in pre-clinical and clinical settings, particularly for diabetic foot ulcers.
October 2025 in “International Journal For Multidisciplinary Research” In this study, researchers documented the use of 69 plant species across 38 families in traditional medicine by herbal practitioners in Raichur District, detailing their therapeutic properties for 22 ailments such as fever, epilepsy, and diabetes, though interest in traditional practices is declining.
April 2025 in “International Journal of Ayurvedic Medicine” This review reports the potential therapeutic effects of Semecarpus anacardium Linn. (Bhallataka), noting its compounds like anacardic acid may have anti-inflammatory, antioxidant, and anticancer properties, but emphasizes that further research is necessary to confirm these effects and determine safety due to inconsistent study methods.
May 2024 in “Drug discovery today” This review discusses the potential role of thyroid receptor β agonists in treating androgenetic alopecia, reporting no new clinical results while highlighting their mechanism and anti-alopecia efficacy.
January 2024 in “Journal of Natural Remedies” This review identifies recent advances in cholangiocarcinoma research, emphasizing the potential of alkaloids to induce apoptosis and inhibit cellular spread in cancer cell lines, offering insights into future therapeutic compound development.
December 2023 in “Health economics and management review” In this descriptive research conducted in Tirunelveli City, Tamil Nadu, the study identified common health problems among radiographers, including tiredness, body pain, and emotional disturbances, highlighting the need to address these issues to ensure accurate disease diagnosis and treatment in healthcare settings.
December 2023 in “Journal of Volgograd State Medical University” This study reviewed current research on white, brown, and beige adipose tissue, highlighting their roles in metabolism, thermogenesis, tissue repair, and stem cell activity, and identified the study of adiponectins as important for advancing knowledge of metabolic syndrome and tissue regeneration mechanisms.
October 2023 in “Journal of Drug Delivery Science and Technology” This review highlights the emerging potential of electrospun nanofibers in promoting hair growth for androgenetic alopecia, showcasing their advantages like high porosity and antibacterial activity, and the possibility of integrating active pharmaceuticals.
January 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers observed that after mesenchymal cell division in mouse and chicken embryonic skin, elevated migration speed and persistence for 180 minutes contribute to mesenchymal dispersal and preferential recruitment to dermal condensates.
October 2022 in “CRC Press eBooks” This review explores the botany, traditional uses, phytochemicals, and pharmacological activities of Cinchona pubescens but presents no new clinical findings.
November 2021 in “Research Outreach” Low testosterone levels may lead to more severe COVID-19 outcomes.
June 2021 in “International Journal of Ayurveda and Pharma Research” This conceptual paper proposes evaluating the Ayurvedic formulation Moorvadi choornam for alleviating side effects of chemotherapy, including symptoms consistent with Garavisha lakshanas, but reports no clinical outcomes.
January 2021 in “Journal of Cancer Therapy” This study described the safety profile of tyrosine kinase inhibitors in treating various solid tumors, finding that the observed toxicities were consistent with existing literature.
November 2020 in “Journal of Bioengineering and Technology Apllied for Health” This review discusses the mechanisms, symptoms, and body system damage caused by SARS-CoV-2, emphasizing the complexity of treatment and suggesting more research is needed to fully understand COVID-19.
June 2020 in “Journal of cosmetic medicine” This abstract reviews eyebrow transplantation techniques, highlighting that follicular unit extraction prevents scarring at the donor site, unlike strip harvesting, and reports no new clinical results.
December 2019 in “Journal of Cosmetic Dermatology” In this study, researchers developed an innovative training model using oranges to practice designing the scalp's parietal whorl for hair transplantation. They reported that a density of 40-50 follicular units per cm² achieved better results, aiding surgeons in improving their technique.
January 2019 in “Jui rinsho hifuka” This study reported that a 12-year-old neutered male Siberian husky dog showed resolution of alopecia, pyoderma, and diarrhoea after thyroidectomy and thyroid supplementation for a functional thyroid carcinoma.
This study reported that various medications, including known agents like finasteride and testosterone as well as unexpected ones like certain psychotropics and statins, are linked to male infertility cases in the Vigibase database.
January 2017 in “SM dermatology journal” This article presents eyebrow transplantation techniques developed from over 1,000 procedures at the authors' clinic, with no new clinical outcomes reported.