research Hair Biology
The document explains hair biology, the causes of hair loss, and reviews various hair loss treatments.
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research Androgenic Hormone Profile of Adult Women with Acne
Over half of the adult women with acne in the study had higher than normal levels of male hormones, especially DHEA.
research Formulation and Optimization of Transfersome Containing Minoxidil and Caffeine
Minoxidil and caffeine in transfersomes improve hair growth treatment.
research Effect of Dihydrotestosterone on the Upregulation of Inflammatory Cytokines in Cultured Sebocytes
Dihydrotestosterone increases certain inflammatory signals in skin cells, potentially contributing to acne.
research Androgens Induce Sebaceous Differentiation in Sebocyte Cells Expressing a Stable Functional Androgen Receptor
Androgens cause oil-producing skin cells with androgen receptors to mature and produce more oil.
research Effect of Citrullus Colocynthis Schrad Fruits on Testosterone-Induced Alopecia
Citrullus colocynthis fruit extract may effectively treat testosterone-related hair loss, similar to finasteride.
research The Effect of 5-Reductase Inhibitors on Erectile Function
5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.
research Clinical Relevance of Testosterone and Dihydrotestosterone Metabolism in Women
Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.
research Prevention and Treatment of Experimental Prostate Cancer in Lobund-Wistar Rats: Effects of Estradiol, Dihydrotestosterone, and Castration
Estradiol and castration reduced prostate cancer development in rats when applied at early stages, but were ineffective after cancer was established.
research Alopecia and the Metabolic Syndrome
Men with common hair loss may have a higher risk of heart disease and diabetes, and should be checked for these conditions.
research Androgen Receptor Accelerates Premature Senescence of Human Dermal Papilla Cells in Association with DNA Damage
Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.
research Gas Chromatography/Mass Spectrometry Based Hair Steroid Profiling May Reveal Pathogenesis in Hair Follicles of the Scalp
Analyzing hair with this method can help understand and monitor scalp conditions and treatment effects.
research Lack of Androgen Receptor Transcriptional Activity in Human Keratinocytes
Human keratinocytes do not naturally respond to androgens.
research The Basic Science of Hair Biology
Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.
research Novel Agents for the Treatment of Alopecia
New treatments for hair loss show promise, especially finasteride for men and a stronger minoxidil formula.
research Bone Density Is Normal in Male Rats Treated with Finasteride
Finasteride doesn't affect bone density in male rats.
research Hormone-Dependent Medial Preoptic, Lumbar Spinal Cord, and Autonomic Coordination Supporting Male Sexual Behaviors
Testosterone and its byproducts help support male sexual behavior through different pathways in the brain and body.
research Hedonic Sensitivity to Natural Rewards Is Affected by Prenatal Stress in a Sex-Dependent Manner
Prenatal stress changes how male and female rats enjoy rewards differently, linked to sex hormones.
research Ketoconazole as an Adjunct to Finasteride in the Treatment of Androgenetic Alopecia in Men
Ketoconazole shampoo with finasteride improves hair density in men with hair loss.
research Hormonal Prevention of Prostate Cancer
Suppressing certain hormones might help prevent prostate cancer.
research Hair Growth Promoting Effect of White Wax and Policosanol from White Wax on the Mouse Model of Testosterone-Induced Hair Loss
White wax and policosanol from white wax effectively reduced hair loss and promoted hair growth in mice better than a known hair growth drug.
research The mRNA for Protease Nexin-1 is Expressed in Human Dermal Papilla Cells and its Level is Affected by Androgen
Human skin cells contain Protease Nexin-1, and male hormones can decrease its levels, potentially affecting hair growth.
research Roles of Type 10 17beta-Hydroxysteroid Dehydrogenase in Intracrinology and Metabolism of Isoleucine and Fatty Acids
This enzyme helps metabolize fatty acids and isoleucine, and could be key in treating neurological diseases and certain cancers.
research Inhibitory Activities of Some Traditional Chinese Herbs Against Testosterone 5α-Reductase and Effects of Cacumen Platycladi on Hair Regrowth in Testosterone-Treated Mice
Certain Chinese herbs, especially Cacumen platycladi, can promote hair regrowth and reduce hair loss-related hormone levels in mice.
research Regulation Mechanisms of Hair Growth
Hair regrowth slows with age and can be affected by treatments that change enzyme activity in the skin.
research Metabolism and Action of Androgen in the Skin
Androgens affect skin conditions like acne and hair loss through specific biochemical pathways.
research Serenoa Repens Extracts Promote Hair Regeneration and Repair of Hair Loss in Mouse Models by Activating TGF-β and Mitochondrial Signaling Pathway
Serenoa repens extract helps regrow hair and repair hair loss by activating certain cell growth pathways.
research Role of 5α-Reductase Inhibitors in Benign Prostatic Diseases
5α-reductase inhibitors help shrink the prostate, improve urinary symptoms, and may reduce prostate cancer risk.
research The Role of Androgen Therapy
Androgens, male hormones, play a role in both men and women's health, and testosterone therapy can help women with low levels, but it's not suitable for pregnant or lactating women, or those with certain conditions.
research 5α-Reductase Inhibitors/Finasteride: A Safe and Effective Treatment for Benign Prostatic Hyperplasia
Finasteride is a safe and effective long-term treatment for prostate enlargement, reducing prostate volume and related symptoms.