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      Acne: Hormonal Concepts and Therapy

      research Acne: Hormonal concepts and therapy

      118 citations , September 2004 in “Clinics in Dermatology”
      This review discusses the role of hormones in acne vulgaris and highlights the need for further research on their mechanisms of action; it reports no new clinical results.
      Hormonal Therapies for Acne

      research Hormonal therapies for acne

      26 citations , October 2016 in “Clinics in Dermatology”
      This article discusses various hormonal therapies for acne and provides practical treatment guidelines for managing hormonally related acne, but it reports no new research findings.
      Fundamentals

      research Fundamentals

      November 2018 in “Springer eBooks”
      Finasteride and minoxidil are effective, low-risk treatments for male hair loss, and patient education on these therapies is important.
      Role of 5α-Reductase in Health and Disease

      research 9 Role of 5α-reductase in health and disease

      101 citations , April 1994 in “Baillière's clinical endocrinology and metabolism”
      This review discusses the role of 5α-reductase enzymes in androgen action and related disorders, noting that their specific inhibitory drugs show promise for conditions like benign prostatic hypertrophy; it reports no new clinical results.
      Alopecia: Managing the Basics

      research Alopecia: managing the basics

      July 2015 in “Cambridge University Press eBooks”
      The document concludes that treatments for female hair loss and excess body hair are available, but managing expectations is important.
      Acne

      research Acne

      81 citations , January 2002 in “American journal of clinical dermatology”
      Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.
      Clinical Relevance of Testosterone and Dihydrotestosterone Metabolism in Women

      research Clinical relevance of testosterone and dihydrotestosterone metabolism in women

      31 citations , January 1995 in “˜The œAmerican journal of medicine”
      This article reviews the role of 5α-reductase in cutaneous hyperandrogenism and the potential of 5α-reductase inhibitors and antiandrogens in treating conditions like hirsutism and male-pattern baldness, reporting no clinical results.
      Therapeutic Androgen Receptor Ligands

      research Therapeutic Androgen Receptor Ligands

      16 citations , January 2003 in “Nuclear Receptor Signaling”
      Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.
      Antiandrogen Therapy for Androgenetic Alopecia

      research Antiandrogen therapy for androgenetic alopecia

      14 citations , April 2006 in “Expert Review of Dermatology”
      This review discusses therapeutic options for androgenetic alopecia, noting that while antiandrogen treatments prevent further hair loss and promote some regrowth, dramatic results are rare.
      Hair Aging And Anti-Aging

      research Hair aging and anti-aging

      3 citations , October 2007 in “Expert Review of Dermatology”
      This review discusses the biological and cosmetic aspects of hair aging and reports no new clinical results; it highlights current treatments and future research directions to address both aging factors.
      Androgen Receptors And Their Biology

      research Androgen receptors and their biology

      66 citations , January 2001 in “Vitamins and hormones”
      This chapter reviews the role of androgen receptors in mediating the actions of androgens in specific tissues and provides no new experimental findings.
      Idiopathic Hirsutism: Androgen Role and Treatment Options

      research Idiopathic Hirsutism*

      47 citations , August 2000 in “Endocrine Reviews”
      This review discusses idiopathic hirsutism, potential underlying mechanisms, and various therapeutic approaches without providing new clinical results, and emphasizes the need for further research on well-defined patient groups.
      Novel Type 1 5a-Reductase Inhibitors With Antiproliferative Potential On LNCaP Cells

      research Novel type 1 5a-reductase Inhibitors with Antiproliferative Potential on LNCaP cells

      June 2023 in “Oriental Journal of Chemistry/Oriental journal of chemistry”
      This study demonstrated that derivatives of dehydroepiandrosterone (2a-b, 3a-f, and 4a-f) significantly reduced viable LNCaP prostate cancer cells, suggesting potential therapeutic use for metastatic prostate cancer, while finasteride did not alter cell viability.
      Male Androgenetic Alopecia

      research Male androgenetic alopecia

      54 citations , July 2002 in “Clinical and Experimental Dermatology”
      This article provides a critical overview of recent discoveries in the genetics and molecular processes involved in androgenetic alopecia, focusing on its polygenic basis and DHT dependency, but reports no new clinical results.
      Sexual Hormones in Human Skin

      research Sexual Hormones in Human Skin

      305 citations , February 2007 in “Hormone and metabolic research”
      This review discusses the roles of androgens and estrogens in skin functions and disorders, and highlights the use of estrogen-progestin treatments and anti-androgens in managing hirsutism and acne, without reporting new results.
      Finasteride

      research Finasteride

      86 citations , July 1993 in “Drugs”
      Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.
      Androgenic Effects on Ventricular Repolarization

      research Androgenic Effects on Ventricular Repolarization

      64 citations , August 2019 in “Circulation”
      This study found that men receiving enzalutamide and other androgen-deprivation therapies may be at increased risk for QT prolongation and torsades de pointes.