Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

In this study, a new emulsion containing CBD and ginger root extract significantly reduced symptoms of dry and eczema-prone skin, such as erythema and itching, in a clinical trial.

This study developed and validated a method using UPLC-PDA and LC-Q-TOF/MS to identify and measure prohibited substances in dietary supplements, showing reliable detection of compounds like minoxidil and finasteride.

Accurate method measures finasteride levels in human plasma using gas chromatography-mass spectrometry.

In this study, researchers investigated the formation of spherical crystals of minoxidil in various alcoholic solvents, discovering new types like spherulite aggregates and a unique butterfly-shaped crystal, with the spherulite aggregates showing improved powder flow properties compared to other forms.

A girl's hair loss from a pharmacy error improved after getting the right medicine.

This study found that both fluoxetine and clomipramine are effective in treating psychogenic triggers of acral lick dermatitis in dogs, with fluoxetine leading to quicker recovery and lower recurrence rates, while clomipramine showed better overall recovery rates but was associated with fewer side effects.

In this study, oral dienogest combined with ethinylestradiol provided effective contraception with a Pearl Index of approximately 0.2 and improved androgenic symptoms without significant metabolic effects.

This study found that the extract of Eclipta prostrata L. demonstrated high antioxidant and anti-acetylcholinesterase activities, moderate inhibition of enzymes linked to diabetes, and favorable ADMET properties, suggesting potential cognitive and diabetes management benefits.

This study reported the development of two highly sensitive ELISA assays to detect banned substances finasteride and dutasteride in human urine, offering better sensitivity than existing HPLC/MS/MS methods.

This study observed that low-dose oral minoxidil and topical minoxidil 5% solution both improved hair density in women with female-pattern hair loss, but oral minoxidil may offer advantages in reducing hair shedding.

Deuruxolitinib improves anxiety and depression in severe alopecia areata patients.

This study reported that encapsulating minoxidil in transferosomes and transethosomes can enhance skin permeability and drug retention compared to its conventional formulation, potentially increasing efficacy in androgenic alopecia treatment while reducing side effects, especially when transethosomes contain oleic acid.

This study identified a weak interaction between minoxidil and ß-cyclodextrin in solution, forming an inclusion complex with a 1:1 molar ratio.

This congress summary highlights the COMEF 2023 event, which focused on medical ethics, education, and health through discussions with the theme "Learn, practice, excel," but reports no new research findings.

Low-dose oral minoxidil is effective and satisfying for treating hair loss in young people.

This study identified potent dual inhibitors of 5α-reductases 1 and 2 that may aid in designing new drugs for related diseases.

This study found that the synthetic thyroid hormone receptor modulator KB2115 significantly prolonged the growth phase of human hair follicles in culture without altering mitochondrial activity, suggesting potential as a safer hair loss treatment compared to traditional thyroid hormones.

This study found that taxifolin glycosides isolated from Rhododendron mucronulatum showed promise for developing treatments for male pattern hair loss by inhibiting DHT production and enhancing hair growth-promoting factors.

In this report, a participant in a Portuguese pharmacy master's program detailed their six-month internship at Farmácia Queija Ferreira, highlighting their involvement in medication preparation, creating educational resources, and studying drug interactions, including serious cases involving diclofenac and brimonidine.

This study found that systemic administration of NDP-MSH, a melanocortin receptor agonist, provided neuroprotective effects on dopaminergic nigrostriatal neurons in a mouse model of Parkinson's disease, reducing neuroinflammation and suggesting a role for regulatory T cells in these neuroprotective effects.

This study reported that derivatization with 5-butylpicolinic acid improved the sensitivity for detecting testosterone and DHT in saliva using LC-ESI-MS/MS, with minimal interference from the saliva matrix.

This study found that a new hybrid compound designed from finasteride and epristeride was a potent inhibitor of 5α-reductase with a mechanism similar to finasteride.

In an animal study, researchers observed that a newly synthesized deoxycholic acid derivative showed similar prostate protection effects to finasteride in Wistar rats while being less toxic.

In this study, researchers found that 2 out of 9 analyzed cosmetic hair growth products contained the banned substance minoxidil, demonstrating the presence of this antihypertensive drug in some cosmetics despite regulations.

This study developed a precise and sensitive HPLC-MS/MS method for analyzing the pharmacokinetics of perospirone hydrochloride in human plasma, establishing it as suitable for clinical studies.

This study synthesized and evaluated hydroxycinnamate derivatives for their ability to inhibit human SRD5A1, finding that three compounds showed significant inhibitory activity and low cytotoxicity. Compound 10a notably reduced SRD5A1 protein expression in cells, suggesting potential for nonsteroidal treatment of androgen-related conditions.

This study reports that Elvitegravir, a drug currently approved for other uses, shows potential as a neuro- and mitoprotective agent by attenuating mitochondrial damage caused by NMDA receptors in primary mouse cortical neurons.

In this study, a needle-free supersonic atomizer delivering Bacopa monnieri extract with hyaluronan was found to enhance hair growth in mice more effectively than the traditional smear method and minoxidil.

This study used computational methods to identify pranlukast and mirabegron as promising candidates for repurposing against diabetes due to their good binding interactions with the DPP-IV target.

This study found that concentrations of haloperidol and its metabolite in human scalp hair significantly correlated with the daily dose and plasma trough levels in patients taking haloperidol.