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research Suppression of spermatogenesis with desogestrel and testosterone pellets is not enhanced by addition of finasteride.
In this randomized study of male contraceptive regimens, adding finasteride did not significantly enhance spermatogenesis suppression compared to the control group.
research A Dispute Between the Cavendish and Caltech: The Emergence and Ubiquity of the α-Helix
This review details the development of the alpha-helix model for protein structure proposed by Pauling and Corey and confirms its validity through X-ray studies of myoglobin and lysozyme.
research Clinical comparison of extended-release divalproex versus delayed-release divalproex: pooled data analyses from nine trials
In this study, divalproex sodium extended-release was found to be more tolerable and preferred by patients compared to the delayed-release formulation, with improved seizure control and psychiatric symptom relief.
research Allosteric interactions prime androgen receptor dimerization and activation
This study uses cryo-electron microscopy to reveal how androgen receptor forms a non-obligate dimer to bind DNA, with implications for prostate cancer development.
research Metabolism of androgens by isolated human hair follicles
This study observed that male human hair follicles metabolized dehydroepiandrosterone (DHA) more intensively than skin did and found altered DHA metabolism in follicles from balding individuals.
research Oral Testosterone With and Without Concomitant Inhibition of 5α-Reductase by Dutasteride in Hypogonadal Men for 28 Days
This study found that combining oral testosterone with dutasteride increased testosterone bioavailability in hypogonadal men while suppressing dihydrotestosterone levels over a 28-day period.
research Clinical and dermoscopic evaluation of red light emitting diodes with beta-carotene versus red light emitting diodes alone in treatment of photoaging
This study found that combining red light therapy with oral beta-carotene significantly improved photoaging treatment outcomes compared to red light therapy alone, with Group A showing a 56.12% reduction in photoaging scores over 12 weeks versus 44.78% in Group B.
research Management of pregnancy in a carrier of the Donohue mutation
This paper discusses the management of pregnancy in a carrier of the Donohue mutation and reports no new clinical findings.
research 17α-Acetoxy-6-bromo-16β-methylpregna-4,6-diene-3,20-dione
This study describes the molecular conformation and intermolecular interactions in the crystalline structure of the compound C24H31BrO4.
research Androgen biosynthetic pathways in the human prostate
This review outlines the complexities of understanding DHT biosynthesis and metabolism in the human prostate and reports no new findings, emphasizing the need for further research into the pathways involved.
research Trichothiodystrophy: Current Concepts
This study explains that while trichothiodystrophy and xeroderma pigmentosum share genetic defects, TTD patients primarily exhibit issues in transcription initiation, not the increased skin cancer risk seen in XP.
research A Randomized Trial of Oral DHEA Treatment for Sexual Function, Well-Being, and Menopausal Symptoms in Postmenopausal Women with Low Libido
In this study, 50 mg/day of DHEA supplementation in postmenopausal women did not significantly improve sexual function compared to a placebo over 26 weeks.
research Direct quantitative digital autoradiography of testosterone metabolites in the pilosebaceous unit: an environmentally advantageous trace radioactive technology
This paper details a method for measuring testosterone metabolism into seven androgens using digital autoradiography, which offers high sensitivity and reduces the need for radioactive materials.
research De novo single-nucleotide and copy number variation in discordant monozygotic twins reveals disease-related genes
This study found genetic variations, including de novo variants and copy number variations, that may be associated with phenotypic discordance in monozygotic twins with various clinical conditions.
research Efficacy of intramuscular injections of biotin and dexpanthenol in the treatment of diffuse hair loss: A randomized, double‐blind controlled study comparing two brands
This study found that a 6-week treatment with both brands of biotin and dexpanthenol significantly improved hair fall count and hair density in people with diffuse pattern hair loss, with no significant difference between the two brands.
research Methodology and Challenges to Recruitment to a Randomized, Double-Blind, Placebo-Controlled Trial of Oral DHEA in Postmenopausal Women
This study found that recruiting healthy naturally menopausal women for a DHEA therapy trial was challenged by concerns about hormonal treatments and time constraints, impacting study feasibility.
research Doxazosin + finasteride in BPH with TPV ??? 25mL
research In vitrometabolism of dehydroepiandrosterone and testosterone by canine hair follicle cells
This study found that canine dermal papilla cells and fibroblasts metabolize androgens differently than human hair follicle cells, indicating species-specific differences in androgen metabolism.
research Marked Suppression of Dihydrotestosterone in Men with Benign Prostatic Hyperplasia by Dutasteride, a Dual 5α-Reductase Inhibitor
This study found that dutasteride more effectively reduced serum dihydrotestosterone levels than finasteride in patients with benign prostatic hyperplasia.
research Effects of ultra violet radiation on the soluble proteins of human hair
This study found that UV radiation exposure increased protein elution and altered protein characteristics in hair fibers, suggesting environmental factors impact hair shaft proteins.
research Anabolic effect of dihydrotestosterone in testicular feminization syndrome
In this study, patients with testicular feminization syndrome showed limited anabolic responsiveness to dihydrotestosterone, potentially due to reduced affinity of nuclear receptor sites for androgenic steroids rather than defective testosterone conversion.
research A homozygous nonsense mutation identified in COL7A1 in a family with autosomal recessive dystrophic epidermolysis bullosa
In this study, researchers identified a recurrent nonsense mutation, c.409C>T (p.Arg137*), in the COL7A1 gene through whole exome sequencing in a family with autosomal recessive dystrophic epidermolysis bullosa, demonstrating the importance of this method for diagnosing genetically complex conditions.
research GPRC6A-Duox1 Axis Regulates the Hair Cycle Through H2O2 Generation
This study found that the GPRC6A-Duox1 signaling pathway influences hair cycle progression and testosterone-mediated hair loss in mice, suggesting that disruption of this pathway leads to resistance against testosterone-induced hair loss and longer anagen phase duration.
research Bestellen hondrostrong für osteochondrose Frankfurt
This abstract contains fragmented and promotional text about various topics, including Hondrostrong and unrelated products, without presenting any new research findings.
research Solubilizing steroidal drugs by β-cyclodextrin derivatives
This study found that anionic HSES achieved high complexation efficiencies with various steroids, significantly enhancing their solubility, while specific β-cyclodextrin thioethers showed selective binding to testosterone and estradiol.
research Dehydroepiandrosterone for women in the peri- or postmenopausal phase
This review found no evidence that DHEA improves quality of life or decreases menopausal symptoms in peri- and postmenopausal women, but it may slightly enhance sexual function compared to placebo.
research Re: Effect of Testosterone Supplementation With and Without a Dual 5α-Reductase Inhibitor on Fat-Free Mass in Men with Suppressed Testosterone Production: A Randomized Controlled Trial
This abstract reviews testosterone supplementation with and without a dual 5α-reductase inhibitor on fat-free mass in men with suppressed testosterone production and reports no new research findings.
research Depo-Provera: an injectable contraceptive.
This article reviews the contraceptive agent Depo-Provera, discussing its effectiveness, potential side effects, and safety concerns, but reports no new clinical results.