Depo-Provera: An Injectable Contraceptive

    January 1982 in “ PubMed
    S Wigington
    TLDR Depo-Provera effectively prevents pregnancy but has many side effects and safety concerns, leading to its ban in the U.S.
    Depo-Provera, an injectable contraceptive, was effective in preventing ovulation and had additional contraceptive effects such as thickening cervical mucus and altering tubal ovum transport. A 150 mg dose every 3 months was as effective as the combined oral pill. However, it had numerous side effects, including menstrual disorders, hair loss, and potential long-term risks like cancer. Its use was controversial due to safety concerns, leading to its ban in the U.S. The document recommended against its long-term use and suggested focusing on developing safer contraceptives without systemic side effects.
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