126 citations,
October 1983 in “Journal of The American Academy of Dermatology” Isotretinoin effectively treats severe acne and similar conditions, but has common, mostly reversible side effects, requiring careful patient monitoring.
124 citations,
December 2016 in “Pharmaceuticals” TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.
116 citations,
February 2017 in “Journal of the American Academy of Dermatology” JAK inhibitors help with skin conditions but need more research on dosing and safety.
105 citations,
January 2010 in “Mediators of Inflammation” Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.
104 citations,
March 1987 in “Journal of The American Academy of Dermatology” Minoxidil helps hair growth in 63.6% of alopecia patients, with 27.3% having excellent results.
85 citations,
May 2001 in “International Journal of Dermatology” Skin diseases differ between Ghana and the UK, with infections most common in Ghana and malignant skin diseases most prevalent in the UK.
80 citations,
June 2012 in “European Journal of Pharmaceutics and Biopharmaceutics” Nanoparticles improve drug delivery and effectiveness in treating inflamed skin.
75 citations,
May 2013 in “Journal of the American Academy of Dermatology” Zinc deficiency in children can cause skin issues and can be serious if not diagnosed and treated properly.
74 citations,
July 1979 in “Lancet” Biotin treatment can significantly improve hair loss and motor functions in certain metabolic disorders.
72 citations,
October 1988 in “Archives of Disease in Childhood” Biotin treatment improves symptoms of biotinidase deficiency, but some neurological damage may be permanent.
70 citations,
May 2014 in “JAMA Dermatology” The representation of skin conditions in medical reviews partly matches their real-world impact.
67 citations,
January 2022 in “Theranostics” Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.
57 citations,
June 2018 in “Nutrients” Celiac disease can cause skin problems that may get better with a gluten-free diet.
57 citations,
February 2018 in “Journal of the American Academy of Dermatology” Biotin supplements are not proven to improve hair or nails and may interfere with medical tests.
54 citations,
June 2018 in “Nutrients” Early diagnosis and a strict gluten-free diet are crucial for children with celiac disease to improve symptoms.
50 citations,
March 2000 in “American Journal of Clinical Dermatology” Alopecia Areata has no guaranteed treatment for hair regrowth, but options like corticosteroids and minoxidil are used, with future research focusing on genetic and immune therapies.
49 citations,
July 1994 in “British journal of dermatology/British journal of dermatology, Supplement” Some children with methylmalonic and propionic acidaemias have skin problems related to their condition and diet.
48 citations,
October 1996 in “Dermatologic clinics” Some treatments can help with hair regrowth in alopecia areata, but results vary and long-term use is often needed without changing the disease's outcome.
43 citations,
October 1955 in “The journal of nutrition/The Journal of nutrition” Germ-free rats need biotin for growth and have different vitamin metabolism compared to regular rats.
42 citations,
August 1987 in “Archives of Dermatology” Squaric acid dibutylester led to complete hair regrowth in 28.5% of patients with alopecia areata.
40 citations,
January 2010 in “Indian Journal of Dermatology, Venereology and Leprology” Certain diets can affect skin conditions, but more research is needed to understand these relationships fully.
35 citations,
April 1937 in “The journal of nutrition/The Journal of nutrition” Flavin prevents cataracts in young rats.
32 citations,
March 2021 in “Journal of endocrinological investigation” Thyroid hormones are important for skin health and changes in them can affect conditions like hair loss and eczema.
32 citations,
April 2000 in “Dermatologic Clinics” Skin diseases, especially psoriasis, greatly affect people's quality of life, similar to chronic diseases.
30 citations,
January 2013 in “Obesity Surgery” Bariatric surgery affects skin health, causing both direct complications and changes in existing skin conditions, often related to nutritional deficiencies.
30 citations,
November 2008 in “Facial Plastic Surgery” The conclusion is that the best approach for treating Female Pattern Hair Loss is a combination of different treatments.
26 citations,
November 2016 in “Current pharmaceutical design” Ginseng may be beneficial for skin health and treating various skin conditions.
26 citations,
February 1978 in “Journal of Pediatric Surgery” Long-term TPN in children can cause zinc deficiency, leading to health issues.
22 citations,
August 1940 in “The journal of investigative dermatology/Journal of investigative dermatology” Rats with a pellagra-like skin condition were cured by a vitamin found in yeast, later identified as vitamin B6.
21 citations,
September 2016 in “Journal of Dermatological Treatment” The new classification system for skin disorders emphasizes the importance of understanding a patient's awareness of their condition for better treatment.