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This review discusses advancements in the use of microneedle arrays and nanoparticles for transdermal delivery of therapeutics, noting challenges in overcoming the skin barrier and summarizing recent clinical trial achievements in areas like cancer therapy and gene therapy.

This review discusses the use of derma rollers for cosmetic purposes and their potential in transdermal drug delivery by summarizing evidence on their design, efficacy, safety, and concerns from preclinical and clinical reports.

This review discusses the application of active transdermal technologies in cosmetic devices for skin restoration and enhancement, reporting no new clinical results.

This review summarizes the positive clinical response of using platelet-rich plasma as an adjuvant in skin rejuvenation treatments, with no identifiable complications, suggesting a promising outlook for its future use.

This study found that microneedling combined with calcipotriol plus betamethasone was more effective in treating vitiligo than microneedling with tacrolimus, particularly in difficult-to-treat areas.

This study demonstrated that customized microneedle arrays can precisely induce targeted hair regeneration and improve hair quality in mice, potentially offering a personalized treatment approach for hair loss.

In this study, iL-PRF injections produced significantly better clinical scores for androgenetic alopecia patients compared to controls, especially in those with more severe baseline conditions.

This review discusses the use of microneedling for androgenetic alopecia and finds it promising for enhancing hair density and thickness, especially when combined with other treatments, but notes no standardized protocol exists yet.

This review discusses the emerging pathophysiological factors and potential new therapies for androgenetic alopecia beyond traditional treatments, but reports no new results.

This retrospective pilot study found that oral tofacitinib was more effective in treating alopecia areata than alopecia universalis, but relapses were common after treatment cessation.

ChatGPT can be a helpful dermatology resource but should not replace professional consultations.

In this pilot study, both microneedling and CO2 laser combined with hair transplantation and nbUVB demonstrated potential for inducing repigmentation in refractory palmar-plantar vitiligo, though further research is needed to ascertain their relative efficacy.

This study proposes an innovative treatment for stretch marks by combining skinbooster and microneedling techniques, which induce tissue remodeling and collagen synthesis, and suggests using confocal microscopy as a valuable tool for monitoring skin changes in aesthetic dermatology.

This study found that fractional Er:YAG laser combined with platelet-rich plasma resulted in greater skin repigmentation in patients with localized stable vitiligo compared to microneedling with platelet-rich plasma, with fewer side effects reported in the laser group.

This study found that adding platelet-rich plasma with microneedling to conventional medical treatment significantly increased hair density and diameter in androgenetic alopecia patients compared to medical treatment alone.

The study found that a single autologous micrografting treatment using Rigenera® technology significantly improved the appearance of stretch marks in healthy women after three months, showing greater enhancements in skin properties compared to microneedling alone.

In this study, PRP was found to show promise in treating melasma, offering consistent positive outcomes and satisfaction rates among patients, especially when combined with treatments like hydroquinone and tranexamic acid, though further research is needed to confirm long-term efficacy and safety.

This study concluded that stromal vascular fraction treatment was effective in increasing hair density and thickness in patients with androgenetic alopecia over a three-month period.

This review discusses various types of microneedles and their potential to expand the range of drugs delivered via the skin, but reports no new clinical results.

This case report observed that microneedling combined with topical minoxidil significantly increased hair growth in an elderly man with severe androgenetic alopecia compared to minoxidil alone.

This review highlights the potential of microneedles as a low-cost, well-tolerated method for transdermal drug delivery in dermatology, though further research is needed to establish their clinical efficacy.

This review summarizes late-breaking abstracts from the American Society for Laser Medicine and Surgery, 2018, and reports no new clinical findings.

This review evaluates PRP, microneedling, and LLLT for alopecia and telogen effluvium, reporting improvements of 30-40% but offers no new clinical data.

In this systematic review, researchers found that nanotopical systems like nanoparticles and liposomes significantly improved hair density, thickness, and follicular regeneration markers in alopecia treatment, sometimes surpassing traditional therapies like topical minoxidil, though methodological limitations remain such as insufficient long-term clinical trials.

In this case report, researchers describe a 44-year-old woman with refractory patch alopecia areata achieving complete hair regrowth using a multi-modal approach of systemic and topical cholecalciferol with microneedling, although systemic vitamin D repletion remains a significant confounder.

This article highlights India's suitability as a strategic location for dermatology clinical trials due to its diverse patient population and cost-effective environment, offering insights on optimizing trials through advanced diagnostics, regulatory compliance, and ethical governance to attract global sponsors.

This review suggests that combining Platelet-Rich Plasma and microneedling may enhance hair restoration outcomes in patients with androgenetic alopecia compared to using either therapy alone.

This review explores the potential of microneedling as a drug delivery system for treating melasma, focusing on its mechanisms, safety, efficacy, and clinical advantages over conventional therapies like hydroquinone and lasers.

This review concludes that platelet-rich plasma is a promising treatment for androgenetic alopecia, enhancing hair density and thickness, though outcomes vary due to differences in preparation and application methods.

In this study, plasmatherapy was found to improve immune status indicators in patients with vitiligo, particularly benefiting those with segmental vitiligo by normalizing immune markers and reducing IL-6 levels, suggesting its potential as an adjunct treatment to slow depigmentation progression.