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900-930 / 1000+ results![Microenvironmental reprogramming by three-dimensional culture enables dermal papilla cells to induce de novo human hair-follicle growth](/images/research/6c53bfba-3548-42a2-ab7a-0e6298c19396/small/12845.jpg)
research Microenvironmental reprogramming by three-dimensional culture enables dermal papilla cells to induce de novo human hair-follicle growth
Growing human skin cells in a 3D environment can stimulate new hair growth.
![Androgen‐inducible TGF‐β1 from balding dermal papilla cells inhibits epithelial cell growth: a clue to understanding paradoxical effects of androgen on human hair growth](/images/research/3570e3d5-d828-4d92-9063-0190fd57fd67/small/28172.jpg)
research Androgen‐inducible TGF‐β1 from balding dermal papilla cells inhibits epithelial cell growth: a clue to understanding paradoxical effects of androgen on human hair growth
Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.
![Dihydrotestosterone-Inducible Dickkopf 1 from Balding Dermal Papilla Cells Causes Apoptosis in Follicular Keratinocytes](/images/research/ee116f10-3c87-4db2-a2b8-178a8b84a856/small/15070.jpg)
research Dihydrotestosterone-Inducible Dickkopf 1 from Balding Dermal Papilla Cells Causes Apoptosis in Follicular Keratinocytes
A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.
![Liposomal systems as drug delivery vehicles for dermal and transdermal applications](/images/research/ac489b5f-b140-4292-9986-8dd353c43b03/small/14744.jpg)
research Liposomal systems as drug delivery vehicles for dermal and transdermal applications
Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.
![Extracellular vesicles derived from MSCs activates dermal papilla cell in vitro and promotes hair follicle conversion from telogen to anagen in mice](/images/research/659bd426-d4e2-4fb1-9150-60809194439b/small/18098.jpg)
research Extracellular vesicles derived from MSCs activates dermal papilla cell in vitro and promotes hair follicle conversion from telogen to anagen in mice
Tiny particles from stem cells help activate hair growth cells and encourage hair growth in mice without being toxic.
![Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis](/images/research/84cc8c1b-d56d-4a06-92c5-e2512740a3c1/small/22039.jpg)
research Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis
Laminin-511 is crucial for early hair growth and maintaining important hair development signals.
research Applications and limitations of lipid nanoparticles in dermal and transdermal drug delivery via the follicular route
Lipid nanoparticles can help deliver drugs through hair follicles but struggle to penetrate deeper skin layers.
![Oxidative Stress–Associated Senescence in Dermal Papilla Cells of Men with Androgenetic Alopecia](/images/research/15c9b147-ee17-4ce3-9473-6405533715ba/small/3595.jpg)
research Oxidative Stress–Associated Senescence in Dermal Papilla Cells of Men with Androgenetic Alopecia
Oxidative stress affects hair loss in men with androgenetic alopecia.
![Minoxidil activates β-catenin pathway in human dermal papilla cells: A possible explanation for its anagen prolongation effect](/images/research/19a70bcf-3786-47a6-a50c-50e455713423/small/3056.jpg)
research Minoxidil activates β-catenin pathway in human dermal papilla cells: A possible explanation for its anagen prolongation effect
Minoxidil helps hair growth by activating the β-catenin pathway.
![Inhibition of β-catenin signalling in dermal fibroblasts enhances hair follicle regeneration during wound healing](/images/research/268062b8-21f1-46eb-ba51-7fd4600da189/small/3862.jpg)
research Inhibition of β-catenin signalling in dermal fibroblasts enhances hair follicle regeneration during wound healing
Blocking β-catenin in skin cells improves hair growth during wound healing.
![Liposomes and niosomes as potential carriers for dermal delivery of minoxidil](/images/research/081c1c1d-d6ec-49c6-9a4f-ea9de78fd664/small/2712.jpg)
research Liposomes and niosomes as potential carriers for dermal delivery of minoxidil
Liposomes better deliver minoxidil for hair loss treatment than niosomes.
![Hair follicles’ transit-amplifying cells govern concurrent dermal adipocyte production through Sonic Hedgehog](/images/research/e7b97f69-b9e9-4664-bd83-a4378b3d3064/small/19590.jpg)
research Hair follicles’ transit-amplifying cells govern concurrent dermal adipocyte production through Sonic Hedgehog
Cells in hair follicles help create fat cells in the skin by releasing a protein called Sonic Hedgehog.
![Alteration of Skin Properties with Autologous Dermal Fibroblasts](/images/research/7efb4c99-3e34-43c5-9e4b-928f3a523912/small/12825.jpg)
research Alteration of Skin Properties with Autologous Dermal Fibroblasts
Using your own skin cells can help repair aging skin and promote hair growth.
![Different gene expression profile observed in dermal papilla cells related to androgenic alopecia by DNA macroarray analysis](/images/research/354dfd6e-a280-4d3b-8194-9a0c6b3da8c1/small/12334.jpg)
research Different gene expression profile observed in dermal papilla cells related to androgenic alopecia by DNA macroarray analysis
Hair loss in balding individuals is linked to changes in specific hair growth-related genes.
![The stretched scar: the benefit of prolonged dermal support](/images/research/36ee55bb-1f33-4cba-84e8-a5ea3f2931ca/small/21153.jpg)
research The stretched scar: the benefit of prolonged dermal support
Leaving non-absorbable sutures in for 6 months reduces scar stretching and width.
research Epidermal growth factor promotes proliferation of dermal papilla cells via Notch signaling pathway
A substance called epidermal growth factor helps increase the growth of important hair follicle cells by activating a specific cell communication route.
![Maintaining Hair Inductivity in Human Dermal Papilla Cells: A Review of Effective Methods](/images/research/751791bf-251a-4e1a-ae8d-a481bf4f6ad5/small/17538.jpg)
research Maintaining Hair Inductivity in Human Dermal Papilla Cells: A Review of Effective Methods
The review concluded that keeping the hair-growing ability of human dermal papilla cells is key for hair development and growth.
![Paracrine crosstalk between human hair follicle dermal papilla cells and microvascular endothelial cells](/images/research/cd260aa5-2341-449a-83c1-1af0b6b6d954/small/18684.jpg)
research Paracrine crosstalk between human hair follicle dermal papilla cells and microvascular endothelial cells
Cells from the base of hair follicles help blood vessel cells survive and grow, which is important for healthy hair.
![Fate of Prominin-1 Expressing Dermal Papilla Cells during Homeostasis, Wound Healing and Wnt Activation](/images/research/2b851bce-bd61-4b93-a80a-05e6ae370e5f/small/19650.jpg)
research Fate of Prominin-1 Expressing Dermal Papilla Cells during Homeostasis, Wound Healing and Wnt Activation
Prominin-1 expressing cells in the dermal papilla help regulate hair follicle size and communication but don't aid in skin repair.
![Androgen Receptor Accelerates Premature Senescence of Human Dermal Papilla Cells in Association with DNA Damage](/images/research/d9411813-4369-4dbd-8a53-4c6adcc8d42e/small/18944.jpg)
research Androgen Receptor Accelerates Premature Senescence of Human Dermal Papilla Cells in Association with DNA Damage
Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.
![Culture and Differentiation of Human Hair Follicle Dermal Papilla Cells in a Soft 3D Self-Assembling Peptide Scaffold](/images/research/e82e5e97-0a7f-4c93-a079-ec1d0e9e692d/small/34206.jpg)
research Culture and Differentiation of Human Hair Follicle Dermal Papilla Cells in a Soft 3D Self-Assembling Peptide Scaffold
The 3D scaffold helped maintain hair cell traits and could improve hair loss treatments.
![Differential expression analysis of balding and nonbalding dermal papilla microRNAs in male pattern baldness with a microRNA amplification profiling method](/images/research/3d8f00a0-3bf9-46fc-8db0-31c5bc8bb0f3/small/21896.jpg)
research Differential expression analysis of balding and nonbalding dermal papilla microRNAs in male pattern baldness with a microRNA amplification profiling method
Certain microRNAs are more common in balding areas and might be involved in male pattern baldness.
![Reprogramming of Human Hair Follicle Dermal Papilla Cells into Induced Pluripotent Stem Cells](/images/research/87091211-b86c-46fe-a98d-8ee94db1885d/small/12859.jpg)
research Reprogramming of Human Hair Follicle Dermal Papilla Cells into Induced Pluripotent Stem Cells
Human hair follicle cells can be successfully transformed into different types of cells, but not more efficiently than other adult cells.
![Hypoxia improves hair inductivity of dermal papilla cells via nuclear<scp>NADPH</scp>oxidase 4‐mediated reactive oxygen species generation'](/images/research/d2f0c0eb-1017-4c04-8e7a-2a1b415b7312/small/17703.jpg)
research Hypoxia improves hair inductivity of dermal papilla cells via nuclearNADPH oxidase 4‐mediated reactive oxygen species generation'
Low oxygen levels can make hair-growing cells better at growing hair through a process involving reactive oxygen species.
![Large-scale cultivation of transplantable dermal papilla cellular aggregates using microfabricated PDMS arrays](/images/research/0f3d081b-a688-4356-9955-7af9e2447ab8/small/19881.jpg)
research Large-scale cultivation of transplantable dermal papilla cellular aggregates using microfabricated PDMS arrays
Researchers developed a method to grow hair follicle cells for transplantation using a special chip.
![Activating β-catenin signaling in CD133-positive dermal papilla cells increases hair inductivity](/images/research/d8e81b16-18e0-426c-b2d5-24388b29f77d/small/12782.jpg)
research Activating β-catenin signaling in CD133-positive dermal papilla cells increases hair inductivity
Boosting β-catenin signaling in certain skin cells can enhance hair growth.
![Effect of ethosomal minoxidil on dermal delivery and hair cycle of C57BL/6 mice](/images/research/dcd65daa-5b2c-40d2-a1fb-a6af08b51c8c/small/2711.jpg)
research Effect of ethosomal minoxidil on dermal delivery and hair cycle of C57BL/6 mice
Ethosomal minoxidil improves hair growth by penetrating deeper into skin and shortening hair cycle.
![A guide to studying human dermal adipocytes in situ](/images/research/96120213-3842-4537-9c73-301205b4ae34/small/17919.jpg)
research A guide to studying human dermal adipocytes in situ
The guide explains how to study human skin fat cells and their tissue, aiming to improve research and medical treatments.
![Getting to the Core of the Dermal Papilla](/images/research/3ae74d13-f7d6-4843-8936-ebbcd66f925e/small/13878.jpg)
research Getting to the Core of the Dermal Papilla
The document concludes that understanding dermal papilla cells is key to improving hair regeneration treatments.