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Testosterone therapy may improve mood, well-being, and sexual function in premenopausal women, but more research is needed on its long-term safety and effectiveness.

TGase 3 helps build hair structure by forming strong bonds between proteins.

Aging reduces the ability of human hair follicle cells to form new cell colonies.

Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.

Sleep problems and skin issues affect each other; poor sleep can worsen skin conditions, and some skin treatments can improve or harm sleep quality.

Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.

The protein SLC1A3 is important for activating skin stem cells and is necessary for normal hair and skin growth in mice.

Key genes regulate hair follicle phase changes in Inner Mongolia cashmere goats.

Nanocarrier-loaded gels improve drug delivery for cancer, skin conditions, and hair loss.

Sebaceous glands in the skin play a key role in absorbing the antiandrogen drug RU 58841, especially when it's encapsulated in liposomes.

Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

GPR40 agonists help hair growth through the protein ANGPTL4.

Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.

Different body parts have varying levels of certain hair follicle markers.

The conclusion is that grasping how cells determine their roles through evolution is key, with expected progress from new research models and genome editing.

Minoxidil can be effectively encapsulated in coated nanovesicles for potential drug delivery.

The vitamin D receptor helps regulate skin and hair health independently of its usual vitamin D ligand.

CD4+ skin cells may be precursors to basal cell carcinoma.

Testosterone therapy can help postmenopausal women with low sexual desire but needs more safety research and should be used with estrogen therapy.

Testosterone therapy can help with androgen deficiency in women but should be used with caution and monitoring due to potential risks.

RNA aptamers can specifically block FGF5-related cell growth, potentially treating related diseases or hair disorders.

Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.

Particle properties affect drug retention and release in minoxidil foams, with lipid nanoparticles having higher loading capacity.

Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.

Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.

Intravital imaging helps us better understand stem cells in their natural environment and could improve knowledge of organ regeneration and cancer development.

Diagnosing PCOS in teenage girls is tricky and requires careful evaluation and management.

The document concludes that hair transplantation and gene therapy may be important for future hair loss treatment.

The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.