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Three characteristics of plasmacytoid dendritic cells help tell apart lupus-related hair loss from LPP.

Plasmacytoid dendritic cells, which overproduce IFN-α, may play a crucial role in starting alopecia areata, an autoimmune disease causing hair loss.

Sex and stress steroids quickly change brain cell structures in the hippocampus.

Hair follicles help attract immune cells to minor skin injuries.

Hair follicles help attract immune cells to the skin during stress.

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

Porcine skin is very similar to human skin, making it a useful model for research.

Faulty Notch signalling may cause hair follicle changes and inflammation in hidradenitis suppurativa.

The document concludes that while there are various treatments for Alopecia Areata, there is no cure, and individualized treatment plans are essential due to varying effectiveness.

RXRα is crucial for proper immune response and links diet to immune function.

Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.

The study concluded that immune cells attacking hair follicles cause hair loss in alopecia, with genetics and environment also playing a role, and highlighted the potential of certain treatments.

Frontal fibrosing alopecia is linked to increased immune system activity and reduced stem cells, suggesting early treatment targeting this pathway might prevent hair follicle damage.

A protein called lfTSLP is important in causing allergic and other skin diseases and could be a target for treatment.

Lambs' skin showed similar but more severe responses to a second orf virus infection, involving immune cells and new skin formation.

Melatonin stimulates the skin components of ram's scrotum during their non-breeding season.

Human prenatal skin develops an immune network early on that helps with skin formation and healing without scarring.

Antigen presenting cells around hair follicles are crucial in SLE-related hair loss.

The research reveals how early embryonic mouse skin develops from simple to complex structures, identifying various cell types and their roles in this process.

RANKL improves the immune response against herpes simplex virus by enhancing T cell activation and could help develop better treatments or vaccines.

Melanocytes from human fetal hair follicles were successfully cultured, showing potential for hair disease research and clinical use.

Nitric oxide is important for skin functions and both helps protect against and contributes to skin inflammation and sensitization.

Lack of Evi in skin causes psoriasis-like symptoms in mice.

RIPK1 inhibitors might help prevent alopecia areata.

Canine pemphigus foliaceus involves significant immune activity and shares similarities with human pemphigus.

Early intervention and patient education are crucial for managing alopecia areata.

Reflectance confocal microscopy helped tell periorificial dermatitis apart from similar skin conditions.

COVID-toes show a unique immune response over time, different from vaccine-related chilblains.

Targeting mTOR in myeloid cells may help reduce psoriasis symptoms.