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The conclusion is that new plant-based treatments for hair loss may work by targeting certain enzymes.

A specific metabolite, not a receptor protein, triggers the production of certain kidney enzymes, but this process is disrupted in mice with a mutation causing testicular feminization.

Retinoic acid production and signaling in hair follicles are regulated by location and timing, affecting hair growth and cycling.

A substance called compound-1 could help increase hair growth by maintaining prostaglandin levels in hair follicles.

Taking riboflavin and eating less lysine can help some people with a specific genetic disorder avoid brain damage.

Some women with excess hair growth have a hormone condition that can't be diagnosed by blood or urine tests alone.

Stilbamidine and hydroxystilbamidine inhibit enzyme release from lysosomes and have effects similar to cortisol and chloroquine.

The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

Mice without certain skin enzymes have faster hair growth and bigger eye glands.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

A boy with Sjogren-Larsson syndrome has skin and muscle symptoms due to a specific enzyme deficiency.

The document concluded that more research is needed to understand how estrogen affects the enzyme involved in hirsutism development.

Sebocytes play a key role in controlling androgen levels in human skin.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

Mouse skin can produce and process serotonin, with variations depending on hair cycle, body location, and mouse strain.

Apple polyphenols, especially from unripe apples, can help prevent cells from turning into fat cells.

UV light might cause excessive hair growth by increasing PGE2 in the skin.

Yellow Chinese chive extract helps protect mouse livers from damage caused by acetaminophen by activating an antioxidant pathway.

Autophagy helps activate hair stem cells and hair growth by changing their energy use to glycolysis.

A woman's mature cystic teratoma caused her virilization by producing testosterone.

The document highlights various patents for new compounds with potential treatments for multiple diseases, including cancer, hormonal disorders, and diabetes.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Macrophage activation syndrome can be a deadly first sign of systemic lupus erythematosus.

Deferasirox effectively reduces iron overload in ß-thalassemia patients but may cause some manageable side effects.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Topical finasteride and flutamide reduce gland size and enzyme activity, with flutamide being more potent, potentially treating acne, seborrhea, hirsutism, and androgenic alopecia.

The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.

Lactate production is important for activating hair growth stem cells.