research Novel Androgen Receptor Degrader for Androgenetic Alopecia (AGA) Application
A new treatment for hair loss shows promise with fewer side effects.
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research Protac Degraders of Androgen Receptor-Integrated Dissolving Microneedles for Androgenetic Alopecia and Recrudescence Treatment via Single Topical Administration
A new hair loss treatment using dissolving microneedles was found to speed up hair growth and was more effective than daily use of common hair growth drugs.
research Discovery of a Novel Non-Invasive AR PROTAC Degrader for the Topical Treatment of Androgenetic Alopecia
A new topical treatment for hair loss shows promise by targeting androgen receptors.
research 52243 AH-001: An Emerging Androgen Receptor Degrader Showing Therapeutic Potential in Addressing Androgenetic Alopecia
AH-001 could be a safer and more effective treatment for hair loss.
research Novel Androgen Receptor Degrader for Androgenetic Alopecia Application
research Enzymatic Method for Assessing Hair Damage with Reduction and Subsequent Oxidation
Permed hair degrades faster and shows more damage after protease treatment compared to untreated hair.
research The Degradative Characteristics of Hair in Water Samples with Altered pH
Hair fibers degrade and change color in very basic water.
research Properties of Partially Extracted Hairs and Their Degradability by Proteases
Mf-rich hair degrades more than Ma-rich hair, especially with Proteinase K.
research The Progress of Common Treatments and Research for Androgenetic Alopecia
Androgen receptor degrader drugs may be a promising future treatment for hair loss.
research Stability Studies of Antiandrogenic Compounds in Curcuma Aeruginosa Roxb. Extract
Germacrone in Curcuma aeruginosa extract degrades at high temperatures but is stable in certain solutions and unaffected by pH levels.
research Androgen Receptor Modulators: A Review of Recent Patents and Reports (2012-2018)
New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.
research The Role of Neprilysin in Regulating the Hair Cycle
Neprilysin is important for hair growth regulation.
research Insight into Recent Advances in Degrading Androgen Receptor for Castration-Resistant Prostate Cancer
New treatments targeting androgen receptors show promise for drug-resistant prostate cancer.
research Is Intrafollicular Autophagy an Essential Mechanism That Permits Human Hair Follicles to Remain in Prolonged Anagen In Vivo?
Autophagy, a cell recycling process, is crucial for prolonged hair growth and could be a potential target for treating hair growth disorders.
research Tumor Suppressor Activity of ODC Antizyme in MEK-Driven Skin Tumorigenesis
Antizyme slows skin tumor growth by reducing cell growth in mice.
research ToF-SIMS Characterization of the Lipid Layer on the Hair Surface: The Damage Caused by Chemical Treatments and UV Radiation
Chemical treatments and UV radiation severely damage the lipid layer on hair.
research Co-Drug Strategy for Promoting Skin Targeting and Minimizing the Transdermal Diffusion of Hydroquinone and Tranexamic Acid
HAC and BAC improve skin targeting and reduce diffusion without causing irritation.
research Maintenance of Optimized Hair Growth from Viable Terminal Scalp Hair Follicles at Baseline with Oral Finasteride in Male Pattern Hair Loss and First Evidence of a Drug Dependency and a Post-Finasteride Rebound Effect
Finasteride helps hair growth but stopping it causes faster hair loss.
research Klhl24-Mediated Hair Follicle Stem Cells Structural Disruption Causes Alopecia
A faulty KLHL24 gene leads to hair loss by damaging hair follicle stem cells.
research The Distribution of Melanocytes and the Degradation of Melanosomes in Fetal Hair Follicles
Fetal hair follicles have melanocytes with melanosomes at different stages, which are broken down into pigment particles in keratinocytes.
research Vibrational Raman and IR Data on Brown Hair Subjected to Bleaching
Bleaching hair changes its structure and weakens it, which is important for understanding hair damage and creating treatments.
research Chitosan Hydrogel Dressing Loaded With Adipose Mesenchymal Stem Cell-Derived Exosomes Promotes Skin Full-Thickness Wound Repair
The new Exo/Gel dressing with stem cell-derived particles helps skin wounds heal faster.
research Degradation of Aberrant NETs by DNases as a Therapeutic Strategy for SJS/TEN
Using DNase enzymes to break down harmful NETs could be a new treatment for Stevens-Johnson syndrome and toxic epidermal necrolysis.
research Review on Premature White and Grey Hair in Children
Poor quality hair products contribute to premature greying in children.
research Sebocytes Are the Key Regulators of Androgen Homeostasis in Human Skin
Sebocytes play a key role in controlling androgen levels in human skin.
research Probing the Effects of Stress Mediators on the Human Hair Follicle
Stress-related substance P may lead to hair loss and negatively affect hair growth.
research Skin Connective Tissue and Aging
Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.
research Targeting Cutaneous Cannabinoid Signaling in Inflammation: A Highway to Heal?
Enhancing cannabinoid signaling may help treat skin inflammation.
research Novel Tip-Loaded Dissolving and Implantable Microneedle Array Patches for Sustained Release of Finasteride
New dissolving and implantable microneedle patches have been created for a long-lasting, non-invasive delivery of the drug finasteride.
research The Risk of Hydroquinone and Sunscreen Over-Absorption via Photodamaged Skin Is Not Greater in Senescent Skin Compared to Young Skin: Nude Mouse as an Animal Model
Aging and sun damage do not increase the skin's absorption of certain sunscreens and drugs.