research Clinical Efficacy of Diphenylcyclopropenone in Alopecia Areata: Retrospective Data Analysis of 50 Patients
Diphenylcyclopropenone (DPCP) is effective in treating alopecia areata, with most patients showing significant hair regrowth.
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research Immune Cells in Cutaneous Wound Healing: A Review of Functional Data from Animal Models
Different immune cells like platelets, mast cells, neutrophils, macrophages, T cells, B cells, and innate lymphoid cells all play roles in skin wound healing, but more research is needed due to inconsistent results and the complex nature of the immune response.
research Severe Hair Loss Associated with Psychotropic Drugs in Psychiatric Inpatients—Data from an Observational Pharmacovigilance Program in German-Speaking Countries
Some psychiatric drugs can cause severe hair loss, especially valproic acid, and it's more likely in women or those with thyroid issues or past hair loss.
research Exploring the Potential Routine Use of Electronic Healthcare Record Data to Strengthen Early Signal Assessment in UK Medicines Regulation: Proof-of-Concept Study
Using electronic health records can help identify drug side effects but has some limitations.
research Homology Modeling of 5-Alpha-Reductase 2 Using Available Experimental Data
Accurate protein modeling can help develop new treatments for prostate cancer and other diseases.
research Hidradenitis Suppurativa Encounters in a National Electronic Health Record Database Notable for Low Dermatology Utilization, Infrequent Biologic Prescriptions, and Frequent Opiate Prescriptions
HS patients rarely see dermatologists, often get opiates, and need better care.
research Genetic Prediction of Male Pattern Baldness Based on Large Independent Datasets
New models predict male pattern baldness better than old ones but still need improvement.
research Innovative Sequence of Docetaxel–Gemcitabine Based on Preclinical Data in the Treatment of Advanced Non-Small Cell Lung Cancer: A Phase I Study
The new chemotherapy combination for advanced lung cancer showed a 35.7% response rate but caused significant side effects.
research Are Finasteride-Related Penile Curvature/Peyronie’s Disease Adverse Event Reports Worthy of Further Clinical Investigation? Disproportionality Analysis Based on Both the Food and Drug Administration (FDA) and the European Medicines Agency (EMA) Pharmacovigilance Databases
Finasteride may be linked to Peyronie’s disease, but more research is needed.
research 5-Alpha Reductase Inhibitor Related Litigation: A Legal Database Review
Most legal cases about 5α-reductase inhibitors, drugs for hair loss and prostate issues, complain about side effects and delayed cancer diagnosis, with most lawsuits settled out of court.
research A Hierarchical Bayesian Hidden Markov Model for Multi-Dimensional Discrete Data
Non-denatured soybean extracts are effective for skin care, offering skin lightening, anti-aging, and UV protection benefits.
research Safety and Tolerability of Antiepileptic Drugs in Women with Epilepsy
Antiepileptic drugs can cause side effects like menstrual problems and infertility in women with epilepsy, but most pregnancies result in healthy babies, with newer drugs being safer.
research Finasteride and Male Infertility: A Case for Prospective Collaborative Research Databases
Finasteride discontinuation increases sperm count in men.
research Risk of Suicide, Hair Loss, and Aspiration with Glucagon-Like Peptide 1 Receptor Agonists: A Real-World Pharmacovigilance Study from the FAERS Database
GLP1-RAs may have higher reports of suicide and hair loss, but no strong evidence links them to these issues.
research Genetic Variants in Androgenetic Alopecia: Insights from Scalp RNA Sequencing Data
Certain genetic variants and pathways are linked to hair loss.
research The 100 Most Cited Androgenetic Alopecia Articles: An Analysis of Altmetrics Data from 2015 to 2022
Healthcare professionals are selective in reading, while the public struggles to find reliable dermatology sources.
research Validation of Alopecia Coding in US Claims Data Among Women of Childbearing Age
The algorithm accurately identified alopecia in women of childbearing age using claims data.
research Sentiment Analysis and Natural Language Processing Using Reddit Data to Evaluate Patient Opinions on Hair Loss Therapeutics
People on Reddit generally have positive opinions about hair loss treatments.
research Correction to: An Evaluation of the Federal Adverse Events Reporting System Data on Adverse Effects of 5-Alpha Reductase Inhibitors
The correction states that the label change for Finasteride was in 2012, leading to more reports of side effects from non-healthcare people.
research Hair Analysis Based on Medical History and Spatial-Temporal Data
Hair analysis can provide insights into a person's medical history and location over time.
research Androgenic Effects on Ventricular Repolarization: A Translational Study from Pharmacovigilance Databases to iPSC-Cardiomyocytes
Androgen-deprivation therapies increase the risk of certain heart conditions, but testosterone treatment may help.
research Why Waiting for Godot Could Not Be an Ideal Technique to Generate Scientific Data
Waiting for a perfect study is futile; instead, use a clinical registry and collect data incrementally to improve wound treatment knowledge.
research Melatonin And Hair Physiology: Reasons And Clinical Efficacy Data As A Topical Treatment Of Androgenic Alopecia
Melatonin applied to the scalp helps increase hair density in people with early hair loss.
research Neural Substrates of the Emotional Negativity Bias as Revealed by Hemodynamic Data
Cyproterone acetate is a safe treatment that causes mild feminizing effects in adolescent trans-girls.
research Litigation Associated With 5-Alpha-Reductase-Inhibitor Use: A Canadian Legal Database Review
Canadian lawsuits involving 5-alpha-reductase inhibitors are related to persistent erectile dysfunction side effects, with no judgments against companies yet.
research Investigation of Optimum Transplant and Extraction Density Based on Data from the Donor Area of Chinese Androgenetic Alopecia Patients: A Multicenter, Retrospective Study
Optimal transplant density for Chinese male hair loss patients is 35-50 hair/cm², with minimum 106.88 hair/cm² left in donor area for esthetic satisfaction.
research Assessing Finasteride-Associated Sexual Dysfunction Using the FAERS Database
Finasteride and dutasteride increase sexual dysfunction reports.
research Post Finasteride Syndrome: Demographics from FDA Database
Younger people (median age 35) experience more PFS-like symptoms with 1mg finasteride; more research needed.
research The Effects of Inositol in Female Androgenetic Alopecia: Preliminary Data
research Polycystic Ovary Syndrome, Androgen Excess, and the Risk of Nonalcoholic Fatty Liver Disease in Women: A Longitudinal Study Based on a United Kingdom Primary Care Database
Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.