Semaglutide and Hair Loss: A Real-World Analysis

September 2024 in “ Journal of the American Academy of Dermatology ”

Ruple Jairath, Damien Abreu, Caroline Mann

Semaglutide hair loss weight loss drug clinical trials Barnes Jewish Healthcare system TriNetX database Ozempic

TLDR Semaglutide does not significantly increase the risk of hair loss.

The study investigated the potential link between Semaglutide, a popular weight loss drug, and hair loss. While clinical trials at a higher dose (2.4mg weekly) showed a slight increase in hair loss reports (3% vs. 1% for placebo), real-world data from the Barnes Jewish Healthcare system and the TriNetX database revealed that only 0.80% and 0.83% of patients, respectively, experienced hair loss within six months of starting Semaglutide at 0.25-2mg weekly. These findings suggest that Semaglutide does not significantly increase the risk of hair loss.

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