75 citations,
March 1998 in “Journal of Investigative Dermatology” The transgene likely activated an oncogene or interrupted a tumor suppressor gene, causing melanoma in mice.
73 citations,
December 2015 in “Nature Genetics” Mutations in TBX3 cause horses to have more even hair color instead of Dun camouflage.
71 citations,
May 2006 in “The journal of investigative dermatology/Journal of investigative dermatology” TTD hair brittleness is caused by multiple structural abnormalities.
35 citations,
October 2000 in “Dermatologic clinics” A scarring hair loss condition mainly affects middle-aged women of African descent, impacting their quality of life, with treatments more effective when started early.
12 citations,
January 2014 in “Menoufia Medical Journal” Dermoscopy improves diagnosis of hair and scalp disorders and can help avoid unnecessary biopsies.
3 citations,
January 2017 in “Journal of cardiovascular pharmacology” Re-evaluating minoxidil, reducing sodium intake, and addressing arteriolar hypertrophy can improve hypertension management.
1 citations,
August 2022 in “Chemical engineering journal advances” Scientists made human hair magnetic by coating it with special nanoparticles.
1 citations,
January 2012 in “International journal of trichology” Sheep hair follicle cells can grow a lot but need the dermal papilla to do so.
July 2024 in “Periodontology 2000” Autologous platelet concentrates show promise in esthetic treatments but need more standardized research.
November 2023 in “ACS Omega” New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.
286 citations,
August 2007 in “Journal of Clinical Investigation” Alopecia areata is an autoimmune disease where T cells attack hair follicles.
109 citations,
February 2018 in “CB/Current biology” ERULUS controls root hair growth by regulating cell wall composition and pectin activity.
55 citations,
October 2019 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” The review suggests that other immune cells besides CD8+ T cells may contribute to alopecia areata and that targeting regulatory cell defects could improve treatment.
48 citations,
April 2008 in “Human Molecular Genetics” Progerin affects cell shape but not hair or skin in mice.
43 citations,
December 2017 in “BMC Plant Biology” GmMAX3b gene in soybeans boosts nodulation and affects hormone levels.
30 citations,
September 2016 in “Aging Cell” Low selenium levels can extend lifespan but worsen health issues.
29 citations,
November 2022 in “Nature Medicine” Genetic variations greatly affect individual metabolism and can impact health and disease risk.
29 citations,
October 2020 in “Environmental health perspectives” Five preservatives may disrupt hormone function and need more health and environmental risk assessment.
13 citations,
June 2014 in “Molecular therapy” The lentiviral array can monitor and predict gene activity during stem cell differentiation.
12 citations,
January 2021 in “International Journal of Biological Sciences” Scientists successfully edited a goat's genes to grow more and longer cashmere hair.
10 citations,
February 2014 in “Fitoterapia” Pomiferin may improve skin and hair by increasing important protein production.
9 citations,
October 2017 in “Frontiers in plant science” The peach gene CTG134 helps control the interaction between auxin and ethylene, which could lead to new agricultural chemicals.
8 citations,
June 2023 in “Journal of clinical medicine” Nanofat shows promise for facial rejuvenation and treating skin issues but needs more research for long-term safety.
8 citations,
June 2022 in “Scientific Reports” LGR5 is a common marker of hair follicle stem cells in different animals and is important for hair growth and regeneration.
8 citations,
January 2020 in “International Journal of Trichology” Different patterns on the scalp help diagnose types of hair loss without needing a biopsy.
7 citations,
January 2021 in “Frontiers in genetics” Inherited color dilution in rabbits is linked to DNA methylation changes.
6 citations,
January 2015 in “Evidence-based Complementary and Alternative Medicine” Saw palmetto extract may help treat brain tumors by blocking a specific growth signal and blood vessel formation.
5 citations,
October 2021 in “Frontiers in Cell and Developmental Biology” Fat tissue under the skin affects hair growth and aging; reducing its inflammation may help treat hair loss.
5 citations,
February 2019 in “Neuroscience letters” Hormones during puberty increase certain receptors in the brain, and this change is influenced by estrogen levels.
3 citations,
June 2021 in “Clinical, Cosmetic and Investigational Dermatology” Dermoscopy is an effective tool for accurately detecting skin cancers.