24 citations
,
October 2008 in “PubMed” This article discusses how UV radiation affects hair protein and pigment, destructuralizes keratin, and emphasizes the protective role of melanin, but reports no new clinical results.
22 citations
,
October 2007 in “JDDG Journal der Deutschen Dermatologischen Gesellschaft” In this case study, combination therapy with dapsone and isotretinoin significantly improved perifolliculitis capitis abscedens et suffodiens, with the patient remaining symptom-free for six months on reduced medication.
20 citations
,
January 2022 in “Oxidative Medicine and Cellular Longevity” This study found that intrinsic reactive oxygen species drive the hair follicle cycle progression through DNA damage and repair, apoptosis, and macrophage polarization, influencing hair loss and regeneration dynamics in mice.
20 citations
,
January 1990 in “Journal of dermatological treatment” This study found that both ketoconazole 2% shampoo and selenium sulphide are effective for dandruff treatment, but ketoconazole also reduces hair growth.
20 citations
,
January 1946 in “Journal of Dairy Science” In this study, calves fed skim milk and soybean oil experienced hair loss over the perineal region, which regrew once they began consuming hay or grain, despite continuing the same diet.
19 citations
,
May 2016 in “Clinical, cosmetic and investigational dermatology” In this study, applying FGF-2-containing dalteparin/protamine nanoparticles to the scalp was associated with a significant increase in hair diameter over six months among participants with thin hair.
18 citations
,
October 2017 in “Drug Design Development and Therapy” The study found that finasteride increased endoplasmic reticulum stress and reduced fertility in rats, effects that were alleviated by the administration of DA-9401.
18 citations
,
March 2016 in “Journal of Investigative Dermatology” This study found that calbindin-D9k knockout mice on a maternal vitamin D-deficient and low-calcium diet developed transient alopecia, but a high-vitamin D and calcium diet in mothers reduced this effect.
18 citations
,
January 2015 in “Data series” This report describes a study of estuarine bed-sediment quality in New Jersey and New York post-Hurricane Sandy, focusing on contamination extent and potential long-term impacts, with no new findings included.
17 citations
,
June 2024 in “Journal of the European Academy of Dermatology and Venereology” This study suggests that using an appropriate tool for measuring quality of life is vital, particularly as factors like severity, female sex, and eyebrow involvement may increase the psychosocial burden of alopecia areata.
15 citations
,
December 2000 in “Der Hautarzt” This article reviews causes, symptoms, and current treatments for chronic diffuse hair loss in women, emphasizing the need for further research into the hair cycle's molecular controls but reports no new clinical results.
14 citations
,
July 2021 in “Bioinformatics” This study demonstrates the use of rPanglaoDB, an R package for combining public single-cell datasets, to create the first unbiased transcriptome profile of fibrocytes, revealing their role in tissue healing.
14 citations
,
July 2021 in “Journal of the American Academy of Dermatology” Topical dapsone gel reduced flare-ups in folliculitis decalvans without side effects.
14 citations
,
August 2020 in “Dermatologic Therapy” This study reported that low-dose oral minoxidil is generally safe for treating various types of hair loss, though it may cause hypertrichosis and pedal edema, especially at higher doses.
14 citations
,
February 2013 in “Veterinary dermatology” This study reports that alopecia areata is a rare and typically cosmetic condition in horses, affecting breeds such as Appaloosas and quarter horses, with a possible seasonal pattern of worsening in spring and summer.
13 citations
,
April 2023 in “Nature communications” In this study, researchers used EHR data from two large PCORnet networks to identify a range of long COVID diagnoses, highlighting varying post-acute risks across populations in NYC and Florida.
13 citations
,
April 2022 in “BMC Genomics” This study found that dandruff-afflicted individuals had a less integrated microbial network on the scalp and hair surface compared to healthy individuals, with more positive interactions and unstable connections.
13 citations
,
August 1995 in “British Journal of Dermatology” This study found that dapsone treatment for severe alopecia areata resulted in hair regrowth rates similar to spontaneous recovery, making it significantly less effective than topical immunotherapy.
12 citations
,
December 2017 in “Food and chemical toxicology” This study found that mixtures used in permanent hair dyes had irritant effects on reconstructed human epidermis, while individual ingredients alone did not.
12 citations
,
January 2001 in “Der Hautarzt” This report on a 37-year-old patient found that trichorhinophalangeal syndrome type I is associated with hair abnormalities, including fine and brittle hair with altered biomechanical properties, but no treatment exists for the hair defects.
12 citations
,
October 1981 in “International Journal of Cosmetic Science” This article discusses the disputed role of scalp micro-organisms in dandruff and notes that effective anti-dandruff treatments often have good antimicrobial activity, but it reports no new clinical results.
11 citations
,
January 2017 in “Evidence-based Complementary and Alternative Medicine” This study investigated the effects of the herbal formulation DA-5512 on hair growth, finding that it significantly promotes dermal papilla cell proliferation and stimulates hair growth in mice while showing efficacy and safety in human trials compared to placebo and minoxidil (3%).
11 citations
,
May 2009 in “Clinical and Experimental Dermatology” This case report describes a 12-year-old girl's persistent and worsening scalp condition, ultimately diagnosed as pityriasis amiantacea secondary to localized Darier's disease, after numerous ineffective treatments.
10 citations
,
March 2021 in “International Journal of Environmental Research and Public Health” This study found that Google users are increasingly searching for health information on dermatological issues, with particular interest in itch, hair loss, and skin rash.
10 citations
,
April 2018 in “Journal of Mind and Medical Sciences” This article argues that the mind-body problem is a false issue, proposing that the mind merely temporally associates immaterial data with material support without actual interaction.
10 citations
,
September 2016 in “Journal of cutaneous medicine and surgery” In this prospective study, dabrafenib and trametinib were associated with various skin side effects, including papillomas, hyperkeratosis, and acneiform eruptions in patients with metastatic melanoma.
9 citations
,
June 2020 in “European Radiology Experimental” This study found that single-dose x-ray irradiation in rat calvaria skin led to morphological changes in collagen fibers, disorganization, and a temporary absence of sebaceous glands and hair follicles.
9 citations
,
July 2017 in “Case Reports in Dermatology” This case study describes a 19-year-old female with hidradenitis suppurativa whose symptoms and metabolic abnormalities improved significantly over 3 years on a combined regimen, though some skin lesions persisted.
9 citations
,
April 2024 in “Heliyon” This review highlighted significant properties of probiotics that can promote hair growth and reduce dandruff, offering guidance for future research to scale these findings to pilot studies.
9 citations
,
July 2018 in “International Journal of Dermatology” This study suggests that yellow and white dot signs may be new dermoscopic indicators of advanced androgenetic alopecia in dark-skinned females, with certain trichoscopic features associated with darker skin types.