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Adding a small amount of TPGS to minoxidil can help hair growth, but too much TPGS reduces this effect and increases minoxidil in the blood.

Drug metabolism affects how long a drug works, its interactions, activation, and toxicity, and is influenced by genetics, diet, illness, and other drugs.

Low SULT activity in hair follicles leads to better response to oral minoxidil for hair loss.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

A new method accurately measures nine specific hormones in human blood.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

HSPGs help control stem cell behavior, affecting hair growth and offering a target for hair loss treatments.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

TGF-β2 plays a key role in human hair growth and development.

Over 67 genes linked to ichthyosis help improve diagnosis and treatment.

Minoxidil activates hair growth by being sulfated by P-PST in the human liver.

Mefloquine, an antimalarial drug, is effective in killing melanoma cells resistant to other treatments by causing lethal stress in the cells.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

A peptide known for reducing wrinkles also effectively inhibits an enzyme linked to skin inflammation and acne.

Using a stimulating cream shampoo before applying Minoxidil helps it penetrate hair follicles better, enhancing its hair growth-promoting effect.

Microneedle arrays deliver botulinum toxin effectively for sweat suppression, similar to injections.

Phenylephrine may help prevent hair loss from pulling on the hair roots.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Minoxidil affects cell growth in two ways: low doses increase growth, while high doses slow it down and can be toxic.

Sp6 promotes tooth development by reducing follistatin levels.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.

Minoxidil is processed in the body by an enzyme found in the liver and platelets.

Understanding drug interactions, side effects, and patient-specific factors is crucial for effective dermatological care.

Enzyme purified and characterized for minoxidil sulphation in rat liver.

The enzyme PST is found in developing human kidneys and helps with detoxification and development.

Sulfotransferase SULT1A1 activity may predict minoxidil treatment success for hair loss.

New test predicts if hair loss treatment will work.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.