Impact of a Stimulating Cream Shampoo Treatment on the Penetration of Minoxidil Through Hair Follicles

    May 2016 in “ Journal of Investigative Dermatology ”
    C. Jacques, Camille Genies, V Durosier, Sandrine Bessou-Touya, Hélène Duplan
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    TLDR Using a stimulating cream shampoo before applying Minoxidil helps it penetrate hair follicles better, enhancing its hair growth-promoting effect.
    In 2016, a study was conducted to investigate the impact of a stimulating cream shampoo treatment on the penetration of Minoxidil through hair follicles. The study found that pre-treatment with the stimulating cream shampoo increased the penetration of Minoxidil into the hair follicles and scalp. Specifically, the percentage of Minoxidil recovered into the hair follicles was 0.16% with shampoo pretreatment, compared to 0.06% without. In the scalp, the percentage of Minoxidil reached 2.68% with shampoo, compared to 0.68% without. These results suggest that the stimulating cream shampoo enhances the effect of Minoxidil, a hair growth-promoting agent, by helping it target the hair follicles more effectively.
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