20 citations,
November 2017 in “JAAD case reports” Ustekinumab significantly improved psoriasis, vitiligo, and alopecia areata in a patient.
2 citations,
February 2024 in “International journal of molecular sciences” Gut health affects skin diseases, and probiotics might help.
3 citations,
December 2022 in “Cells” Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.
8 citations,
October 2021 in “Microbiology spectrum” Researchers identified five new potential targets for leishmaniasis treatment, suggesting repurposing existing drugs could be effective.
August 2024 in “Bioscience of Microbiota Food and Health” Microbes might play a role in vitiligo.
1 citations,
May 2009 in “Wiley-Blackwell eBooks” Early treatment of PCOS in teens is crucial to prevent long-term health issues like diabetes and heart disease.
227 citations,
April 2020 in “Cell” More precise, personalized therapies are needed for autoimmune diseases.
17 citations,
September 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Old treatments for other skin conditions showed promise for hair regrowth in mice with a hair loss condition.
May 2023 in “Frontiers in Immunology” Treg cell-based therapies might help treat hair loss from alopecia areata, but more research is needed to confirm safety and effectiveness.
2 citations,
February 2022 in “BioMed Research International” LED light therapy at 863 nm wavelength can slow down skin tumor growth and reduce inflammation in mice.
2 citations,
October 2022 in “Current Allergy and Asthma Reports” Biologic therapies can cause various adverse events, but allergy/immunology clinicians can manage them.
Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.
48 citations,
May 2008 in “Drug Discovery Today: Disease Mechanisms” Hair follicles offer promising targets for delivering drugs to treat hair and skin conditions.
58 citations,
December 2020 in “Mayo Clinic Proceedings” The conclusion is that individual differences in COVID-19 severity are influenced by factors like age, sex, race, and genetics, which are important for personalized medicine.
October 2023 in “Biomaterials” Nanotechnology could improve hair regrowth but faces challenges like complexity and safety concerns.
54 citations,
January 2023 in “Signal Transduction and Targeted Therapy” New therapies are being developed that target integrin pathways to treat various diseases.
April 2017 in “Journal of Investigative Dermatology” Removing the Crif1 gene in mouse skin disrupts skin balance and hair growth.
36 citations,
May 2011 in “Dermatologic therapy” No treatments fully cure or prevent alopecia areata; some help but have side effects or need more research.
35 citations,
October 2017 in “Signal Transduction and Targeted Therapy” Fibromodulin treatment helps reduce scarring and improves wound healing by making it more like fetal healing.
14 citations,
November 2020 in “International Journal of Molecular Sciences” Advanced therapies like gene, cell, and tissue engineering show promise for hair regrowth in alopecia, but their safety and effectiveness need more verification.
8 citations,
December 2017 in “Skin appendage disorders” WNT7A gene expression is higher in early stages of androgenetic alopecia, showing the role of WNT pathway, apoptosis, and inflammation in the disorder.
60 citations,
July 2020 in “ACS Nano” Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.
22 citations,
March 2018 in “American Journal of Clinical Dermatology” New acne treatments show promise as alternatives to traditional therapies.
October 2023 in “Frontiers in endocrinology” Effective PCOS treatments require targeting specific signaling pathways.
October 2023 in “Frontiers in medicine” Targeted immunotherapy could be a promising new treatment for hair regrowth.
15 citations,
November 2020 in “Pharmaceutics” Tofacitinib nanoparticles can safely and effectively treat alopecia areata by targeting hair follicles.
November 2023 in “Linköping University medical dissertations” Keratinocytes and adipose-derived stem cells can effectively heal difficult skin wounds.
April 2017 in “Journal of Investigative Dermatology” Blood cells turned into stem cells can become skin cells similar to normal ones, potentially helping in skin therapies.
3 citations,
January 2024 in “Signal transduction and targeted therapy” Lymphatic vessels are essential for health and can be targeted to treat various diseases.
403 citations,
December 2018 in “Cell stem cell” Understanding phenotypic plasticity is crucial for developing effective cancer therapies.