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The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

Changing how mesenchymal stromal cells are grown can improve their healing abilities.

Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.

The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.

The conclusion is that certain cell interactions and signals are crucial for hair growth and regeneration.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Fat cells help recruit healing cells and build skin structure during wound healing.

JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Stress stops hair growth in mice by causing early hair growth phase end and harmful inflammation through a specific nerve-related pathway.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Some medicinal plants can help heal wounds and may lead to new treatments.

Blocking JAK-STAT signaling can lead to hair growth.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Antibiotics can reduce acne but may lead to resistant bacteria, and understanding the skin's bacteria is important for treatment.

Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.

Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

Fat cells in the skin help start healing and form important repair cells after injury.