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SH-MSCs gel reduced IL-6 and increased TGF-β, suggesting it could treat alopecia.

Excess androgens may cause PCOS, not just be a symptom.

Targeting the HEDGEHOG-GLI1 pathway could help treat keloids.

AP-2α and AP-2β proteins are essential for healthy adult skin and hair.

Skin spheroids with both outer and inner layers are key for regrowing skin patterns and hair.

Hair aging is caused by stress, hormones, inflammation, and DNA damage affecting hair growth and color.

MSC-derived exosomes can help treat COVID-19, hair loss, skin aging, and arthritis.

Drug repositioning offers hope for new, affordable treatments for a genetic skin disorder called ARCI.

Innovative methods are reducing animal testing and improving biomedical research.

Effective PCOS treatments require targeting specific signaling pathways.

JAGGED1 could help regenerate tissues for bone loss and heart damage if delivered correctly.

Higher EULAR/ACR scores in SLE patients predict more organ damage.

Hyaluronic acid and polycaprolactone improve skin regeneration, with polycaprolactone having a stronger effect on healing and tissue repair.

IL-33 is linked to hair follicle damage in psoriasis and could be a treatment target for hair loss in this condition.

Some herbal ingredients like linalool and tea tree oil have anti-dandruff properties and are safe for use in shampoos.

Lower LDL-c levels predict higher COVID-19 mortality.

Repurposing existing drugs for COVID-19 shows promise but requires more research to confirm effectiveness.

Vitamin D is crucial for skin health and managing skin diseases.

Taking vitamin D might improve life for MS patients and reduce skin side effects from alemtuzumab treatment.

Tacrolimus causes fewer acute rejections than cyclosporin A in kidney transplants but doesn't necessarily improve kidney function after one year; cardiovascular risks and side effects vary between the two drugs.

Borneol Essential Oil could be a natural and safe acne treatment.

Plant roots respond to fungus smells by possibly using certain proteins and a plant hormone to change root growth, but more research is needed.

Activating β-catenin increases melanocytes and decreases Schwann cells.

Patients with Systemic Sclerosis have much higher levels of GDF-15, which could help predict organ involvement and guide treatment.

The document is a detailed medical reference on skin and genetic disorders.

Acne can appear or persist in adulthood due to hormonal changes, external factors, or substance use, and requires appropriate treatment.

Acne can be managed with various treatments and requires psychological support due to its emotional impact.

African American women have a higher risk of preterm delivery than Caucasian women, and inflammatory stimuli affect gene expression in cells related to PCOS, showing a heightened inflammatory state in women with PCOS.

Botulinum toxin type A significantly reduces scalp psoriasis severity compared to placebo.

The document concludes that alopecia has significant social and psychological effects, leading to a market for hair loss treatments.