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The conclusion is that formalizing how past decisions influence current health technology assessments could improve the credibility and defense of coverage decisions.

Hairless mice lack fur due to a genetic mutation affecting skin response, not hormone issues.

Women with PCOS have a higher risk of diabetes, heart problems, certain cancers, and mental health issues, but early treatment can help manage these risks.

More PDCD4 is linked to obesity, insulin problems, and cell death in ovaries for those with polycystic ovary syndrome.

Many young Italian women have hyperandrogenic disorders like PCOS, which are linked to age, body weight, and insulin resistance.

New treatments for PCOS show promise, but no current medication treats all aspects of the condition.

Epilepsy and certain epilepsy drugs can lead to reproductive problems in women, but changing medication might improve these issues.

Most dogs with alopecia had higher than normal levels of certain hormones, but hair loss might not always be linked to these hormone changes.

New treatments for immune disorders caused by FOXN1 deficiency are promising.

Doctors should know how to diagnose and treat PCOS, which often involves checking for high male hormone levels and using medications to manage symptoms.

FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.

Extramammary Paget disease can spread deeply into tissues, reaching up to 3.6 mm.

Brazilian women with PCOS and both menstrual irregularity and high male hormone levels have a higher chance of having metabolic syndrome.

Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.

APS-1 in Italy shows diverse AIRE mutations and various autoimmune issues.

Curcumin may improve blood sugar levels and cholesterol in people with PCOS, but more research is needed.

Skin organoids are a promising new model for studying human skin development and testing treatments.

Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.

Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.

The study suggests that being overweight or obese, not PCOS itself, is strongly linked to insulin resistance.

Menopause affects hair and skin; more research needed for treatment.

The document describes a woman with familial Parkinson's disease due to a genetic mutation, showing severe symptoms and poor response to treatment, and suggests finasteride may help reduce symptoms in Tourette syndrome.

LPA3 is crucial for embryo implantation and links LPA to prostaglandin signaling.

Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.

Oral retinoids are effective for treating severe skin disorders but have reversible side effects and risks for pregnant women.

The article concludes that developing in vitro models for human hair structures is important for research and reducing animal testing, but there are challenges like obtaining suitable samples and the models' limitations.

Continuous light exposure in rats leads to PCOS-like symptoms and suggests sleep habits might affect the disorder's development.

A team approach is crucial for managing PCOS, with dermatologists playing a key role.

Diagnosing PCOS in teenagers is hard because its symptoms often look like normal puberty, and there's a need for better diagnosis methods and agreement on criteria.

Thyroid hormones are important for skin health and might help treat skin diseases, but more research is needed to understand their effects fully.