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Compartmentalized organization might be crucial for stem cells to effectively respond to growth or injury.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

In vivo lineage labelling is better than in vitro methods for identifying and understanding stem cells.

Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.

Transplanted hair follicle stem cells can heal damaged rat intestines.

High LGR5 levels in glioblastoma indicate poor prognosis and are essential for cancer stem cell survival.

Stem cell niches support, regulate, and coordinate stem cell functions.

Krt15+ cells in the mouse intestine resist radiation and can start tumors.

The document concludes that stem cell inactivity is actively controlled and important for tissue repair and balance.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

Eating fewer calories improves the ability of stem cells to repair and renew the body in various tissues.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Low-dose radiation affects hair stem cell function and survival by changing their genetic material's structure.

PRC2 is essential for maintaining intestinal cell balance and aiding regeneration after damage.

Targeting colon cancer stem cells might lead to better treatment results.

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

YAP and TAZ are crucial for skin cell growth and repair.

Stem cells regenerate tissues and their behavior varies by environment, suggesting the hematopoietic system model may need revision.

Understanding where cancer cells come from helps create better prevention and treatment methods.

Epithelial stem cells can adapt and help in tissue repair and regeneration.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Stem cell self-renewal is complex and needs more research for full understanding.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Stromal stem cells may help heal wounds by becoming structural cells or affecting the immune system, but more research is needed to understand how.

Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.

Keratin proteins are essential for keeping the cells in the human colon healthy and stable.

Different small areas within hair follicles send specific signals that control what type of cells stem cells become.