131 citations,
March 2004 in “The American journal of pathology” Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.
109 citations,
December 2003 in “American Journal of Pathology” Fetal wound healing changes with development, affecting inflammation and collagen, which may influence scarring.
105 citations,
February 2011 in “The Journal of Clinical Endocrinology & Metabolism” Treating sleep apnea in young obese women with PCOS can improve heart health and insulin sensitivity.
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94 citations,
June 2016 in “The FASEB Journal” The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.
93 citations,
February 2009 in “Annals of the New York Academy of Sciences” 5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.
92 citations,
November 2003 in “The Journals of Gerontology” Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.
81 citations,
May 2007 in “Fertility and Sterility” Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.
77 citations,
June 2006 in “Best Practice & Research Clinical Endocrinology & Metabolism” The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.
76 citations,
June 2015 in “Journal of biomedical science” Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.
72 citations,
November 2012 in “PloS one” The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.
57 citations,
July 2005 in “Clinics in Plastic Surgery” Reconstruct lips with proper planning, templates, and revisions for appearance and function.
53 citations,
January 2012 in “Fertility and Sterility” Women with PCOS are more likely to have sleep apnea, mainly if they are obese.
40 citations,
October 2002 in “Endocrinology” Vitamin D3 analogs can promote hair growth in mice genetically prone to hair loss.
36 citations,
January 2019 in “Nature communications” High lactate dehydrogenase activity is not necessary for the growth of squamous cell carcinoma.
34 citations,
May 2017 in “Seminars in Reproductive Medicine” Women with PCOS have a higher risk of diabetes, heart problems, certain cancers, and mental health issues, but early treatment can help manage these risks.
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30 citations,
May 2004 in “Journal der Deutschen Dermatologischen Gesellschaft” The document concludes that early diagnosis and treatment are crucial for children with hair loss to prevent permanent damage, although not all conditions can be effectively treated.
30 citations,
March 2001 in “Archives of Dermatology” Finasteride can cause one-sided breast enlargement, which disappears after stopping the drug.
27 citations,
July 2017 in “Facial Plastic Surgery” Platelet-Rich Plasma (PRP) shows promise for hair growth and skin improvement in aesthetic surgery.
26 citations,
June 2005 in “Journal of Molecular Endocrinology” Dutasteride is more efficient than finasteride, but individual results vary.
26 citations,
January 1978 in “Nephron” Minoxidil lowers blood pressure effectively but may cause side effects.
25 citations,
February 2017 in “Anticancer Research/Anticancer research” Ozone therapy might improve cancer treatment and reduce its side effects.
25 citations,
July 2008 in “British Journal of Dermatology” CD10 and CD34 levels change during hair development and different hair growth stages, which could be important for hair regeneration treatments.
19 citations,
April 2015 in “Developmental Dynamics” The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.
19 citations,
February 2008 in “Facial Plastic Surgery” The article concludes that microvascular free flaps, especially the latissimus dorsi flap, are recommended for large scalp reconstructions, and hair transplantation offers high survival rates and excellent aesthetic results.
13 citations,
January 2021 in “RSC chemical biology” Wnt activation shows promise for regenerative medicine but requires selective targeting to minimize risks like cancer.
12 citations,
March 2015 in “Pediatric Dermatology” Early diagnosis and treatment of PCOS in young people is important to prevent long-term health problems.
10 citations,
February 2010 in “Journal of Dermatological Treatment” Podcasting could improve dermatology education if it had more consistent, evidence-based content and better regulation.
8 citations,
June 2022 in “Frontiers in bioengineering and biotechnology” A patch made from human lung fibroblast material helps heal skin wounds effectively, including diabetic ulcers.
8 citations,
April 2020 in “Facial Plastic Surgery Clinics of North America” Minoxidil, finasteride, and low-level laser light therapy are effective FDA-approved treatments for hair loss.
8 citations,
June 2011 in “Nature Biotechnology” Stem cell treatments can potentially treat baldness, with one trial showing hair growth after injecting a hair-stimulating complex, and no safety issues were reported.