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Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

The French Endocrine Society suggests diagnosing PCOS with two of three signs, recommends lifestyle changes and clomiphene for treatment, and calls for more research on certain treatments and tests.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Some women with PCOS have CYP21 mutations and IRS1 variants, but these genetic factors are not major contributors to PCOS.

Male hormones affect oil-producing skin cells differently based on their body location, and the drug spironolactone can reduce these effects.

Using fat stem cells and blood cell-rich plasma together improves healing in diabetic wounds by affecting cell signaling.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.

The document suggests using standardized methods to track and measure hair loss in alopecia areata, including patient self-assessment and a 50% improvement in specific scores as a treatment goal.

Low serum complement levels in SLE patients don't always match with disease flares; monitoring C3 and C4 is useful, but cell-bound complement products might better indicate disease activity.

Improved Finasteride delivery for hair loss treatment.

Some people experience severe, long-lasting side effects from fluoroquinolone antibiotics, leading to the recommendation of limited use and increased awareness of these risks.

Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.

Certain genetic variations in the SHBG gene are linked to an increased or decreased risk of PCOS in Mediterranean women.

About 8.5% of women in Salvador, Brazil, have Polycystic Ovary Syndrome.

Skin diseases are very common in poor areas, and there's a need for affordable ways to manage and improve skin health.

SCF and c-Kit decrease in AGA hair follicles, possibly affecting hair pigmentation and growth.

Insulin-lowering medications show promise for PCOS symptoms but can't be the main treatment yet due to limited long-term research.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Blocking CRF-R1 can reduce alcohol intake in stressed mice.

Facial plastic surgery has evolved to focus on less invasive techniques and innovative technologies for cosmetic and reconstructive procedures.

Weight loss and metformin don't significantly change vaspin levels in women with PCOS.

Severe vertex pattern hair loss may indicate a higher risk for artery plaque buildup.

The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.

Women with only irregular periods or excess hair have a better hormone profile than those with full PCOS, but both groups are similar, indicating a need for better PCOS diagnosis methods.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Some treatments like intralesional steroids and 5α-reductase inhibitors are effective for frontal fibrosing alopecia, but more research is needed.

Finasteride treatment in male rats causes long-lasting effects on depression-like behavior, brain cell growth, inflammation, and gut bacteria composition.