Objective Outcome Measures: Collecting Meaningful Data on Alopecia Areata

    Elise A. Olsen, Janet L. Roberts, Leonard C. Sperling, Antonella Tosti, Jerry Shapiro, Amy J. McMichael, Wilma F. Bergfeld, Valerie D. Callender, Paradi Mirmirani, Ken Washenik, David Whiting, George Cotsarelis, Maria Hordinsky
    Image of study
    TLDR The document suggests using standardized methods to track and measure hair loss in alopecia areata, including patient self-assessment and a 50% improvement in specific scores as a treatment goal.
    The 2018 document recommends standardized assessment and response criteria for alopecia areata (AA), highlighting the Severity of Alopecia Tool (SALT) score as the only standardized method at the time. It introduces the Alopecia Density and Extent (ALODEX) score and the Alopecia Areata Progressive Index for more detailed tracking of hair loss and treatment response. The document emphasizes the need for standardized diagnostic criteria, assessment measures, response criteria, and endpoints for AA, including initial and follow-up evaluations. It suggests additional measurements like hair pigmentation and vellus hair coverage, and underscores the importance of patient self-assessment, quality of life instruments, and photographic documentation. A 50% improvement in SALT or ALODEX score is recommended as the primary endpoint for treatment efficacy, with a 12-week evaluation period for new treatments. Despite the challenges in data collection, the document advocates for obtaining basic information to establish best treatment practices for AA.
    Discuss this study in the Community →

    Research cited in this study

    13 / 13 results

    Related Community Posts Join

    6 / 1000+ results
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Why I deleted my YouTube channel Part I

      in Update  118 upvotes 3 years ago
      A YouTuber named Kevin, also known as Rider_Of_Roach, who deleted his YouTube channel due to personal attacks and controversy surrounding his views on hair loss treatments. He advocated for FDA-approved treatments like finasteride and minoxidil but faced backlash from those who disagreed with him. The conversation also discusses his past trolling behavior and a lawsuit he filed against a website that published false information about him. Despite some disagreements, many viewers appreciated his research-based content and hope to see him return in the future.

      community New Treatments, and a Huge Group Buy with Lots of Research

      in Research/Science  109 upvotes 1 year ago
      A user is organizing a group buy for various compounds aimed at reversing hair loss and gray hair, and improving brain health and fat loss. The user has developed a treatment plan based on extensive research and is inviting others to participate, with the option to choose only the compounds they need.

      community Fats on your Head to Stop Hair Loss?

      in Research/Science  138 upvotes 9 months ago
      The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

    Related Research

    3 / 3 results