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The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Isotretinoin effectively treats severe acne and similar conditions, but has common, mostly reversible side effects, requiring careful patient monitoring.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Polycystic Ovary Syndrome likely starts in childhood and may be genetic and influenced by early hormone exposure.

Finasteride effectively inhibits 5α reductase, while plant extracts like Permixon and Bazoton don't show significant results.

Aromatherapy with certain essential oils is a safe and effective treatment for hair growth in alopecia areata patients.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

Insulin sensitizers may slightly reduce hirsutism but are less effective than other treatments.

Minoxidil can help grow hair in mice by making cells grow and improving hair quality. More research needed.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Higher doses of cranial irradiation are linked to permanent hair loss.

Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Rhodococcus equi causes severe pneumonia in young foals, and effective vaccines are needed due to foals' weak immune responses.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

JAK inhibitors help with skin conditions but need more research on dosing and safety.

Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.

The research identified various cell types in mouse and human teeth, which could help in developing dental regenerative treatments.

Platelet-rich plasma (PRP) is a cheap and easy treatment for hair loss, but not suitable for everyone. It also helps in healing ulcers, rejuvenating skin, and improving hair transplants.

Androgens have complex effects on hair growth, promoting it in some areas but causing hair loss in others, and our understanding of this is still evolving.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.

Platelet-rich plasma may help with hair growth and skin quality but more research is needed to confirm its effectiveness.

Wnt and Notch signaling help wound healing by promoting cell growth and regulating cell differentiation.