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Perilla frutescens, an East Asian plant, contains 400 bioactive compounds that have various health benefits, including anti-inflammatory, antidepressant, and anticancer effects, and can treat conditions like diabetes, skin allergies, and neurological disorders.

Blocking neurosteroid production can lead to more seizures and faster epilepsy onset in rats.

Enzymes play crucial roles in metabolism, health, and disease management.

Compound 7b is a promising candidate for treating benign prostatic hyperplasia and prostate cancer.

The research suggests that Tourette syndrome is linked to both brain signaling and immune system pathways.

Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.

Two drugs, ritlecitinib and brepocitinib, improved scalp hair loss condition markers.

Unconventional lymphocytes are important for quick immune responses and healing of skin and mucosal barriers.

The document suggests changing medical education to balance generalists and specialists, focusing on patient needs.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

Tumor suppressors help control inflammation in cancer and restoring their function could lead to new treatments.

Dutasteride makes alcohol less sedating and may lead to less drinking in men.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Hair growth genes work better with more glucose due to changes in gene-regulating markers.

Using 5-alpha-reductase inhibitors may improve bladder cancer survival in men.

The drugs finasteride and dutasteride reduce low-grade prostate cancers but may double the risk of high-grade cancers.

Adding colchicine stopped the girl's recurring heart issues caused by lupus.

Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

Tamsulosin for enlarged prostate may increase the risk of severe low blood pressure, especially when starting or restarting the medication.

Blocking the CXCR3 receptor reduces T cell accumulation in the skin and prevents hair loss in mice.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

TGF-β2 plays a key role in human hair growth and development.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.