32 citations
,
May 2013 in “The Journal of Urology” This study found no statistically significant association between the use of 5α-reductase inhibitors and male breast cancer incidence.
31 citations
,
February 2021 in “Nutrients” This study found that curcumin may improve glycemic control and certain aspects of lipid metabolism in patients with polycystic ovary syndrome.
30 citations
,
November 2018 in “Fertility and Sterility” This study found that young women with polycystic ovary syndrome had a higher risk of developing hypertension and metabolic syndrome compared to healthy controls, although these risks decreased after age 40.
30 citations
,
September 2017 in “Environmental health perspectives” This study found that potential exposure to Corexit™ dispersants during the Deepwater Horizon cleanup was associated with increased respiratory, dermal, and eye irritation symptoms among responders both during the cleanup and up to three years later.
30 citations
,
September 2016 in “BMJ” This study found that 5-α reductase inhibitors do not significantly increase the risk of erectile dysfunction in men with benign prostatic hyperplasia or alopecia, although duration of benign prostatic hyperplasia may elevate risk.
30 citations
,
March 2015 in “Clinical Endocrinology” This study found that late adolescent and young women with clinical hyperandrogenism, including PCOS, experienced higher psychological distress and impaired well-being compared to their healthy peers.
29 citations
,
March 2023 in “European Journal of Human Genetics” This study identified four new genetic loci associated with acne risk and highlighted key pathways involved in its genetic predisposition, potentially explaining 9.4% of acne's phenotypic variance.
29 citations
,
January 2021 in “Translational Psychiatry” This study found that certain gene sets, including those involved in ligand-gated ion channel signaling and cell adhesion, are associated with Tourette syndrome, suggesting a potential neurobiological basis for the disorder.
29 citations
,
July 2020 in “Journal of The American Academy of Dermatology” In this study, researchers found that severe androgenic alopecia in hospitalized men was associated with a higher likelihood of testing positive for COVID-19.
29 citations
,
April 2019 in “BMJ. British medical journal” This study concluded that men with benign prostatic hyperplasia receiving steroid 5α-reductase inhibitors, such as dutasteride or finasteride, have a higher risk of developing new onset type 2 diabetes compared to those taking tamsulosin.
29 citations
,
February 2016 in “International Journal of Dermatology” This study found that patients with lichen planus were significantly more likely to have dyslipidemia, particularly with higher triglyceride levels.
28 citations
,
January 2021 in “Parkinsonism & related disorders (Online)/Parkinsonism & related disorders” This article reviews skin disorders in Parkinson's disease, highlighting the potential of skin studies and stem cell research to advance understanding and treatment of the neurodegenerative disorder, without presenting new results.
28 citations
,
June 2010 in “European Journal of Cancer” This study found that androgenic alopecia at an early age was associated with a lower risk of prostate cancer, contrary to assumptions about androgens' role.
28 citations
,
November 2003 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study indicates that the normal human prostate is not a major contributor to circulating blood DHT concentrations in androgen-deficient patients receiving testosterone replacement therapy.
27 citations
,
June 2023 in “Nature” In this study using genetic mouse models, researchers discovered that senescent melanocytes in nevi secrete osteopontin, which activates hair stem cells, enhancing hair growth; this process is mirrored in human hairy nevi, suggesting a potential therapeutic target for regenerative disorders.
27 citations
,
October 2020 in “Experimental Dermatology” This study found that both extensive grey hair and alopecia were independently associated with increased COVID-19 severity among survey respondents in Brazil.
27 citations
,
September 2017 in “Journal of Medicinal Food” In this study, researchers found that a polyphenolic extract from Annurca apples, high in procyanidin B2, increased hair growth, density, and keratin content in healthy subjects after 2 months of use, and stimulated keratin biosynthesis in vitro.
27 citations
,
July 1990 in “International Journal of Dermatology” In this controlled study, a pulsed electrical field treatment significantly increased hair regrowth compared to baseline and the control group over 36 weeks, without observed side effects.
26 citations
,
December 2020 in “Nature metabolism” Martin-Perez et al. show that rapamycin's beneficial effects in a mouse model of Leigh syndrome are linked to the downregulation of protein kinase C.
26 citations
,
January 2013 in “BMJ Open” This meta-analysis reports that vertex baldness is associated with an increased risk of coronary heart disease, particularly in younger men, while no significant link was found for frontal baldness.
25 citations
,
October 2020 in “Journal of Racial and Ethnic Health Disparities” This study found that zip codes in Oakland County, MI with larger Black populations were disproportionately affected by COVID-19, experiencing higher incidence rates, though racial composition was not linked to case fatality.
25 citations
,
May 2020 in “Stem Cells Translational Medicine” In this randomized clinical trial, the authors reported that adipose-derived stem cell constituent extract topical solution increased hair density and thickness in patients with androgenetic alopecia over 16 weeks compared to placebo.
24 citations
,
November 2015 in “Annals of Nutrition and Metabolism” This study found that specific SHBG gene variants and haplotypes are associated with polycystic ovary syndrome, suggesting that SHBG may be a candidate gene for the condition.
24 citations
,
May 2010 in “Veterinary dermatology” This study found that both ciclosporin A and topical therapy were effective in reducing alopecia and scaling in dogs with idiopathic sebaceous adenitis, with evidence suggesting improved outcomes when both treatments are combined.
23 citations
,
January 2024 in “Nature Immunology” This study, using multimodal profiling in mice, found that various tissues contain unique γδ T cell subsets adapted to their environment, revealing their functional diversity, lineage relationships, and similarities to CD8+ tissue-resident memory T cells.
23 citations
,
August 2017 in “Scientific Reports” Darker hair may lead to higher cortisol readings, suggesting a need to adjust for hair color in studies.
23 citations
,
January 2003 in “Journal of Pediatric Endocrinology and Metabolism” This study observed that the use of hormonal hair products remains common among US Army School personnel, with higher use rates among non-white, female, and enlisted individuals.
22 citations
,
March 2019 in “Environmental health” This study observed that higher childhood fluoride exposure was associated with delayed pubertal development in Mexican boys aged 10-17, with no significant effects found in girls.
22 citations
,
January 2019 in “Endocrinology and metabolism” This study found that among Filipino women, a modified Ferriman-Gallwey score of 7 or above indicates hirsutism and is significantly associated with elevated calculated free testosterone.
20 citations
,
August 2016 in “International Journal of Cancer” This study reports that male-pattern baldness may be linked to an increased risk of skin cancer, particularly for tumors located on the scalp.