research Intracellular Protons Accelerate Aging and Activate Aging Hallmarks in Mice
Acid inside cells speeds up aging and turns on aging signs in mice.
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30 / 600 resultsresearch Novel Anti-Aging Gene NM_026333 Contributes to Proton-Induced Aging via NCX1 Pathway
The gene NM_026333 slows down aging by affecting the NCX1 pathway and could be targeted for anti-aging treatments.
research Molecular Regulation and Cellular Heterogeneity in Skin Repair and Hair Follicle Regeneration
Ovol2 is crucial for hair growth and skin healing by controlling cell movement and growth.
research Transforming Growth Factor-Beta in Stem Cells and Tissue Homeostasis
TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
research Skin Physiology in Microgravity: A 3-Month Stay Aboard ISS Induces Dermal Atrophy and Affects Cutaneous Muscle and Hair Follicles Cycling in Mice
A 3-month stay in space causes skin thinning, disrupts hair growth, and changes muscle-related genes in mice.
research Current Genetics in Hair Diseases
Genetic mutations cause various hair diseases, and whole genome sequencing may reveal more about these conditions.
research Genome Scan for Signatures of Adaptive Evolution in Wild African Goat (Capra Nubiana)
Wild African goats have genetic adaptations for surviving harsh desert conditions.
research Toll-Like Receptor 4 (TLR4): New Insights into Immunity and Aging
TLR4 is important in aging-related diseases and could be a new treatment target.
research Forsythiasides: A Review of the Pharmacological Effects
Forsythiasides have multiple health benefits but may cause pseudoallergic reactions, and more research is needed.
research In Vitro Assembly and Structure of Trichocyte Keratin Intermediate Filaments
Scientists successfully created mouse hair proteins in the lab, which are stable and similar to natural hair.
research The Hair Follicle as an Estrogen Target and Source
Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.
research 17β-Estradiol Inhibits the Production of RANTES in Human Keratinocytes
17β-estradiol can reduce inflammation in the skin.
research The Multifaceted Functions of TRPV4 and Calcium Oscillations in Tissue Repair
TRPV4 helps cells repair tissue and reduce scarring by controlling calcium levels.
research Lignans and Neolignans: Plant Secondary Metabolites as a Reservoir of Biologically Active Substances
Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.
research Biomaterials Functionalized with MSC Secreted Extracellular Vesicles and Soluble Factors for Tissue Regeneration
Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.
research Therapeutic Anti-Inflammatory Potential of Formyl-Peptide Receptor Agonists
Formyl-peptide receptor agonists could be new anti-inflammatory drugs.
research Emerging Roles of Transit-Amplifying Cells in Tissue Regeneration and Cancer
Transit-amplifying cells are crucial for tissue repair and can contribute to cancer when they malfunction.
research An Intrinsic Oscillation of Gene Networks Inside Hair Follicle Stem Cells: An Additional Layer That Can Modulate Hair Stem Cell Activities
Gene network oscillations inside hair stem cells are key for hair growth regulation and could help treat hair loss.
research Stem Cells in the Skin
Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.
research Novel Inhibitors of 5α-Reductase
New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.
research Synthetic Approaches for Pharmacologically Active Decorated Six-Membered Diazines
The document concludes that specific methods for making diazine-based drugs can lead to high yields and are important for creating effective treatments for various diseases.
research Non-Surgical Modalities of Facial Rejuvenation and Aesthetics
Non-surgical treatments like thread lifts, PRP therapy, HIFU, and radiofrequency effectively rejuvenate and tighten facial skin.
research Pioneer Factors Govern Super-Enhancer Dynamics in Stem Cell Plasticity and Lineage Choice
Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.
research Prostaglandin Metabolism in Human Hair Follicle
Human hair follicles can make and process prostaglandins, which may affect hair growth.
research The JAK/STAT Signaling Pathway: From Bench to Clinic
The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
research Drug Delivery System Based On Minoxidil Nanoparticles Promotes Hair Growth In C57BL/6 Mice
Minoxidil nanoparticles can potentially be a more effective treatment for hair growth than current treatments.
research The Rho GTPase Exchange Factor Vav2 Promotes Extensive Age-Dependent Rewiring of the Hair Follicle Stem Cell Transcriptome
Vav2 changes how hair follicle stem cells' genes work as they age, which might improve regeneration but also raise cancer risk.
research Overexpression of Hypoxia-Inducible Factor-1α in Hidradenitis Suppurativa: The Link Between Deviated Immunity and Metabolism
Increased HIF-1α is linked to the inflammation and severity of hidradenitis suppurativa, suggesting treatments that lower HIF-1α could help.
research Whole Exome Sequencing in Alopecia Areata Identifies Rare Variants in KRT82
Rare changes in the KRT82 gene are linked to a higher risk of Alopecia Areata.
research Quercitrin Stimulates Hair Growth with Enhanced Expression of Growth Factors via Activation of MAPK/CREB Signaling Pathway
Quercitrin may help treat hair loss by promoting hair growth and improving cell health.