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Costovertebral arthritis can cause chronic back pain in SLE patients and needs thorough evaluation.

Niosomes are a promising, stable, and cost-effective drug delivery system with potential for improved targeting and safety.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.

Skin problems in COVID-19 patients are rare and may be due to the body's complex immune response or blood clotting issues.

Niosomes are promising for skin drug delivery, offering benefits like improved drug penetration and stability.

Nanoparticulate systems improve drug delivery by controlling release, protecting drugs, changing absorption and distribution, and concentrating drugs in targeted areas.

New drug delivery methods can make natural compounds more effective and stable.

Herbal nano-formulations show potential for effective skin delivery but need more research.

Vesicular carriers like liposomes may improve cosmetic skin treatment delivery and effectiveness but need more human research.

Researchers developed a nanomedicine for acne treatment that delivers medication with less irritation and is non-irritating for oily skin.

New patents show progress in developing drugs targeting the Wnt pathway for diseases like cancer and hair loss.

Liposomes improve the delivery and effectiveness of cosmetic ingredients but face challenges like cost and stability.

Testosterone conversion to 5α-DHT may not be essential for its effects on the skin.

A 33-year-old woman with PCOS and metabolic syndrome was unusually diagnosed with a bone condition called DISH, suggesting a possible link between these conditions.

Researchers concluded that "spigo nardo" is the Himalayan plant Nardostachys jatamansi, used historically in medicine and cosmetics, now critically endangered.

The document concludes that changing the scalp's microbiome might be a new way to treat hair loss.

A pet rabbit had a skin infection that was cured with ketoconazole.

Nanostructured lipid carriers are effective for treating hyperpigmentation in women aged 30-40.

Cinchonine Nanostructured Lipid Carriers serum safely and effectively stimulates hair growth and increases the number and size of hair follicles.

Lower LDL-c levels predict higher COVID-19 mortality.

Certain genes and nutrients like vitamin D, zinc, and omega fatty acids affect COVID-19 severity and infection risk.

Proretinal nanoparticles are a safe and effective way to deliver retinal to the skin.

Frontal fibrosing alopecia causes hairline recession and eyebrow loss in postmenopausal women.

Some cancer and immune system drugs can cause serious side effects, including heart, lung, nerve, and organ damage, which need careful monitoring and management.

Making platelet-rich plasma gel is cheap, safe, and easy when done by trained professionals.

The conclusion is that women under 35 should start fertility checks after 12 months of trying to conceive, women over 35 after 6 months, and women over 40 should start immediately. The checks should include ovulation status, reproductive tract structure, and male partner's semen evaluation.

I'm sorry, but I can't provide a summary without the content of the document. If you provide the conclusion or main points, I can help summarize them.

Ethosomes can safely and effectively deliver various drugs deep into the skin.

Colchicine might help treat different skin diseases, but more research is needed to confirm its effectiveness and safe dosage.