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New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Insulin sensitizers may slightly reduce hirsutism but are less effective than other treatments.

Melanocyte activity in hair follicles is linked to the hair growth cycle, being active in growth phases and inactive in rest phases.

Minoxidil boosts hair growth by activating PGHS-1.

Finasteride use changes brain chemicals, causing lasting sexual issues and anxiety/depression.

Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.

Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.

PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.

Finasteride treatment in male rats causes long-lasting effects on depression-like behavior, brain cell growth, inflammation, and gut bacteria composition.

Men and women have different levels and production of brain steroids, which may affect their risk for certain brain disorders.

Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Post-finasteride syndrome causes lasting sexual, neurological, and physical side effects in some people after taking finasteride.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Post-finasteride patients show changes in gut bacteria, possibly causing various symptoms.

Dutasteride may protect the brain in early Parkinson's disease.

Gut microbes significantly affect brain steroid levels.

The combination of specific chemicals improves hair density in women.

Finasteride affects SRD5A2 gene pattern, possibly causing lasting side effects.

Finasteride may affect PNMT, causing side effects.

Older thin hair is not just thinner but also has different shape, structure, and stiffness.

Finasteride changes hormone levels and certain proteins in rats, but these effects can be reversed after stopping the drug.

Testosterone and its metabolites affect brain functions and could help treat neurological disorders.

5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.

Melatonin and photobiomodulation are effective for treating Alopecia X in German Spitz dogs.

Finasteride treatment in rats changed the expression of genes related to psychiatric and neurological functions, and these changes persisted after stopping the drug.

Stopping finasteride for male pattern hair loss changes neuroactive steroid levels in the brain and blood.

Progesterone and its metabolites affect myelin protein expression differently in male and female rat Schwann cells.