Janus Kinase Inhibitor as a Therapeutic Option in Alopecia Areata: Case Report

August 2021 in “ Revista Colombiana de Reumatología/Revista Colombiana de Reumatologia ”

Lina María Saldarriaga Rivera, Christian David Marín Giraldo, Fabián Andrés Hernández Velasco

alopecia areata autoimmune condition non-scarring hair loss tofacitinib Janus kinase inhibitor biopsy AA JAK inhibitor

TLDR Janus kinase inhibitors may effectively treat severe alopecia areata unresponsive to other treatments.

This case report discusses a 24-year-old female patient with alopecia areata (AA) who experienced extensive hair loss over four years, unresponsive to various treatments including minoxidil, clobetasol, oral and intralesional corticosteroids, finasteride, and cryotherapy. The study highlights the significant emotional and social impact of AA and the challenges in managing resistant cases. It presents the first reported successful use of the JAK inhibitor tofacitinib in a patient with AA in Colombia, suggesting its potential as an effective treatment option for difficult-to-control AA. Ethical considerations were adhered to, with informed consent obtained, and no conflicts of interest or funding were reported.

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Research cited in this study

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research Health-Related Quality of Life Among Patients With Alopecia Areata: A Systematic Review

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