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The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

Testing basal 17-HP levels is a good way to screen for nonclassic adrenal hyperplasia in women with high androgen levels.

Finasteride effectively treats BPH, but needs more trials to understand potential.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

Stress-related substance P may lead to hair loss and negatively affect hair growth.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Women with PCOS have heart-related issues not because of obesity, but due to insulin resistance and low adiponectin levels.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Women with PCOS have overall higher body fat, not abnormal fat placement, and more insulin resistance.

Hair follicles may soon be used more for targeted and systemic drug delivery.

Pregnancy can cause skin darkening, varicose veins, more sweating, hair growth, hair loss after birth, nail changes, and gum inflammation.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Flutamide effectively reduced excessive hair growth and improved related symptoms in hirsutism patients without significant side effects.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Stress can stop hair growth in mice, and treatments can reverse this effect.

Stress can cause hair loss by negatively affecting hair follicles and this effect might be reversed with specific treatments.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

Many women in southern China have polycystic ovary syndrome, with some symptoms differing from Western women.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

Cyproterone acetate-estrogen most effective for hirsutism, but consider side effects and patient needs.