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Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

Activating Nrf2 protects human hair follicles from oxidative stress and helps prevent hair growth inhibition.

Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

WNT10A helps esophageal cancer cells spread and keep renewing themselves.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

Defective mitochondrial DNA replication causes aging symptoms and increased oxidative damage in mice.

Minoxidil needs activation to work, and minoxidil sulfate helps with hair growth and blood pressure.

New treatments for Hepatitis C show promise but need more research to confirm their safety and effectiveness for clinical use.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

A boy with severe Vitamin D-resistant rickets did not respond to treatment and lacked a common symptom, suggesting a need for alternative treatments.

Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.

Micro-needling effectively improves wrinkles, scars, and hair growth, but proper technique and safety are important.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Eupafolin nanoparticles help protect skin cells from damage caused by air pollution.

TGF-β2 plays a key role in human hair growth and development.

CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Adrenal disorders can cause lasting brain and behavior issues in children.

Food deprivation increases MST enzyme in the brain, possibly affecting energy balance.

Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.

Researchers created a new mouse model for studying Citrullinemia Type I and similar conditions, showing symptoms and treatment responses like those in humans.

Two distinct pathways direct proteins to vacuoles in Arabidopsis, affecting root hair growth and protein targeting.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Tedisamil and glibenclamide affect cromakalim and minoxidil sulphate differently in rat aorta.