282 citations,
October 2006 in “The Journal of Clinical Endocrinology and Metabolism” The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.
June 1972 in “Archives of internal medicine” Androgens play a key role in hair growth.
68 citations,
May 2021 in “Endocrine” People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.
15 citations,
August 2021 in “Reviews in endocrine and metabolic disorders” COVID-19 and hypopituitarism (reduced pituitary gland function) are linked, with the latter's related health issues potentially worsening COVID-19 outcomes, and COVID-19 possibly increasing risk for pituitary complications.
There is no cure for myotonic dystrophy type 1, so treatment focuses on managing symptoms and complications.
21 citations,
July 2019 in “Cardiovascular Research” High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.
September 2005 in “Morecambe Bay medical journal” Insulin resistance plays a key role in PCOS, and lifestyle changes, weight loss, and medications like metformin can help manage it.
17 citations,
June 2019 in “Cellular signalling” Minoxidil helps protect and rebuild elastic fibers in arteries, improving artery function, especially in older females.
January 1982 in “Clin-Alert” Some medications caused temporary health issues that improved after stopping the drugs, but two patients died from liver problems linked to carbamazepine.
86 citations,
July 1990 in “British Journal of Pharmacology” Diazoxide, minoxidil sulphate, and cromakalim relax rat blood vessels by opening K+ channels, with some differences in their actions.
29 citations,
October 1996 in “Toxicology and Applied Pharmacology” Higher minoxidil doses in dogs cause faster heart rate, lower blood pressure, and heart issues.
28 citations,
January 2004 in “British Journal of Pharmacology” Minoxidil protects heart and improves recovery.
56 citations,
November 2016 in “Aesthetic surgery journal” The document concludes that the effectiveness of platelet rich plasma in aesthetic surgery is unclear due to inconsistent reporting and lack of objective measures in studies.
34 citations,
January 1989 in “Toxicologic Pathology” A study found that minoxidil can damage the hearts of dogs and pigs, cautioning its use in humans.
32 citations,
February 2024 in “Growth Hormone & IGF Research” Dihydrotestosterone (DHT) stops hair growth in mice by lowering a growth factor important for hair.
1 citations,
January 2018 in “Indian journal of otolaryngology and head and neck surgery” The new surgery method successfully healed the patient's nasal wound without complications.
January 2015 in “Surgical and Cosmetic Dermatology” Platelet-rich plasma injections are an effective treatment for hair loss with minimal side effects.
3 citations,
April 2022 in “Frontiers in Physiology” Ptch2 plays a key role in controlling stem cell function and the ability to regenerate after birth.
1 citations,
April 2023 in “Animals” Deleting the EDAR gene in Cashmere goats affects genes and proteins related to hair growth.
October 2013 in “Journal of the American College of Cardiology” People with non-dipper hypertension have higher aldosterone levels, more strain on their heart's venous system, and increased risk of endothelial dysfunction.
October 2013 in “Journal of the American College of Cardiology” Blood pressure that doesn't drop at night is linked to worse blood vessel function in people with high blood pressure.
33 citations,
May 1991 in “British Journal of Pharmacology” Cromakalim relaxes various blood vessels, while minoxidil sulphate is more selective; they likely act on different potassium channels.
October 2013 in “Journal of the American College of Cardiology” Higher aldosterone levels in urine are linked to a nondipper blood pressure pattern in healthy people.
October 2013 in “Journal of the American College of Cardiology” Autonomic dysfunction is common in hypertensives but may not cause diastolic dysfunction in resistant hypertension.
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Male-pattern baldness has a weak link to heart disease and some related health conditions.
6 citations,
March 2015 in “Journal of Endocrinological Investigation” Taking both finasteride and dutasteride for prostate issues may raise the risk of heart problems.
57 citations,
January 2004 in “Journal of Endocrinology” Baldness caused by male hormones in female-to-male transsexuals doesn't increase the risk of heart disease.
27 citations,
January 2009 in “Journal of The European Academy of Dermatology and Venereology” Men with a certain type of hair loss (AGA) have higher bad cholesterol and lower good cholesterol levels, making them more likely to get heart disease.
18 citations,
December 2010 in “PubMed” People with early hair loss may have higher insulin levels and a greater chance of developing metabolic syndrome.
Insulin resistance is linked to many health problems and is influenced by diet, genetics, and other factors.