Role of Autonomic Dysfunction and Relation with Diastolic Dysfunction in Resistant Hypertensives
October 2013
in “
Journal of the American College of Cardiology
”
TLDR Autonomic dysfunction is common in hypertensives but may not cause diastolic dysfunction in resistant hypertension.
The document reports on two studies related to hypertension. The first study, involving 223 patients, found that the neutrophil/lymphocyte ratio (NLR) was significantly higher in non-dipper hypertensive patients compared to other groups and that NLR levels were influenced by blood pressure variability, suggesting a potential link to organ damage. The second study, with 87 participants, discovered that autonomic dysfunction was present in both resistant and controlled hypertensives, but it did not correlate with diastolic dysfunction in resistant hypertensives. This indicates that while autonomic dysfunction is a common issue among hypertensives, it may not directly contribute to diastolic dysfunction in those with resistant hypertension.