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This study found that low temperatures and nitrogen deficiency trigger root hair elongation through a molecular mechanism involving the receptor kinase FERONIA and the TOR Complex 1.

This study found that γδ T cells play a role in regulating stromal behavior, influencing the composition and vascularity of fibrotic tissues during the foreign body response.

This study found that AtCEPs in Arabidopsis thaliana play a role in controlling root hair growth by processing EXT proteins, with NAC1 acting to regulate their expression and influence elongation.

In this study, researchers found that the efflux of calcium in root hairs of Arabidopsis thaliana, particularly through the ER-localized ACA2 and ACA7, is crucial for modulating cytoplasmic calcium signals and enabling proper root hair growth, with disruptions leading to impaired elongation.

This study found that Ca²⁺ signaling and peptidylarginine deiminase enzymes play a crucial role in activating neural stem cells in response to injury in zebrafish, suggesting potential therapeutic targets for CNS injuries and cancer.

In this study, researchers developed de novo designed hetero-bifunctional proteins as an alternative approach for targeted protein degradation, successfully targeting BCL-xL for degradation in cells and inducing apoptosis, which may expand the range of addressable E3 ligases and disease targets.

This study presents a two-photon imaging method to visualize low-threshold mechanoreceptor axon terminals in live mouse forepaw skin, enabling repeated high-resolution imaging to study sensory circuits during development and adulthood.

In this study, researchers identified a gene regulatory network in Arabidopsis that controls root hair growth under low-temperature conditions, revealing specific transcription factors and downstream targets that contribute to this growth response despite overall plant development being halted.

This study found that back skin mesenchyme from mouse embryos can induce hair follicle formation even before dermal condensate formation, but R-spondin-1 alone or with a Bmp receptor inhibitor was not sufficient for hair follicle induction.

This study found that in mice, competition for hair follicles guides the organization of follicle-innervating LTMR neurons during early development, with different neuronal subtypes showing varying adaptive responses to increased neuron populations.

This study found that sarcoptic mange significantly decreased vicuña and guanaco populations in San Guillermo National Park, Argentina, likely originating from mange-infected llama introduced nearby, raising the risk of local extinction.

This study discovered that the gene Tfap2b identifies a melanocyte stem cell population in zebrafish, essential for regenerating melanocytes with multi-fate potential into adult pigment cells.

This study identified a new cis-regulatory element in the mouse Hr gene that influences its expression in skin and brain cells, highlighting a complex molecular network involved in hair follicle formation.

This review discusses the significant role of Wnt signaling in skin development, homeostasis, and disease, highlighting recent advances in understanding its diverse functions, but reports no new experimental results.

This review discusses the role of epidermal and other adult stem cells in skin repair, focusing on their potential therapeutic applications for non-healing wounds and other skin disorders, but reports no new research results.

This review examines apoptotic and anti-apoptotic mechanisms in skin homeostasis and related diseases but presents no new research findings.

This study identified an unexpected critical role for the FATP4 protein in skin and hair development in mice, linking it to a potential candidate gene for restrictive dermopathy in humans.

In this study, researchers found that TCDD exposure accelerated differentiation and altered gene expression in human epidermal cells, indicating the epidermal barrier as a target of TCDD-activated AHR.

This review discusses current and emerging drug therapies for treating androgenetic alopecia and alopecia areata, and reports no clinical results; it highlights a need for improved and novel treatments.

This review discusses the complex relationship between stress and various skin conditions, highlighting the role of the skin in the stress response and the brain-skin communication pathways, but reports no new research findings.

This study found that overexpression of the mineralocorticoid receptor in a mouse model led to premature epidermal barrier development, keratinocyte apoptosis, and postnatal alopecia, indicating new roles for MR signaling in skin physiology.

This study found that in scarring alopecia, stem cells are differentially localized, suggesting that both inner and outer root sheath stem cells, rather than just follicular bulge stem cells, are involved.

This study found that ablating centrosomes in developing epidermis alters keratinocyte division without majorly affecting differentiation, suggesting early epidermal development is driven by high proliferation and cell delamination.

This study found that α3β1-integrin is crucial for maintaining normal hair follicle morphology in mice, as its deficiency leads to severe abnormalities despite not affecting interfollicular epidermal differentiation.

This study suggests that deep dermatophytosis is a distinct condition occurring in immunocompromised patients, characterized by nodules, an indolent course, and absence of follicular invasion, which resolves completely with systemic antifungal treatment.

This review discusses changes in keratin structure or gene expression that result in various skin disorders and reports no new clinical findings.

This review discusses how inflammation influences hair follicle stem cell activities like wound healing and follicle cycling and suggests a potential link between inflammation, stem cell activation, and programmed cell death.

In this study, mange lesions with alopecia and crusts in masked palm civets in Japan were caused by the mite Notoedres cati.

This study found that Pannexin 3 plays a crucial role in skin development by regulating the transcription factor Epiprofin, affecting keratinocyte differentiation and hair follicle regeneration in mice.

This study reports that the white rhinoceros has a unique integumentary structure among large herbivores, characterized by thick epidermis, organized collagen bundles, and the presence of coiled sweat glands.