97 citations,
March 2002 in “Molecular and cellular biology” Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.
76 citations,
January 2007 in “American Journal of Clinical Dermatology” Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.
25 citations,
June 2004 in “Journal of Investigative Dermatology” Macrophage-stimulating protein helps hair grow and can start hair growth phase in mice and human hair samples.
356 citations,
December 1986 in “The journal of cell biology/The Journal of cell biology” Hair and nail cells share similar proteins, indicating a common differentiation pathway.
22 citations,
November 2016 in “International journal of molecular sciences” Vitamin D receptor is important for regulating hair growth and wound healing in mice.
Keratin hydrogels from human hair show promise for tissue engineering and regenerative medicine.
1 citations,
March 2004 in “Journal of The European Academy of Dermatology and Venereology” Hair loss improved with treatment and successful transplant.
New insights into cell communication in psoriasis suggest innovative drug treatments.
25 citations,
February 2019 in “Genomics” Cashmere and milk goats have different hair growth cycles and gene expressions, which could help improve wool production.
349 citations,
January 2005 in “The FASEB journal” Human skin can make serotonin and melatonin, which help protect and maintain it.
31 citations,
January 2003 in “Dermatology” Steroidogenic isoenzymes may help improve treatments for common hair loss.
22 citations,
January 2002 in “Treatments in endocrinology” Birth control pills help treat skin and hair growth problems linked to high male hormone levels.
33 citations,
December 2012 in “NMR in Biomedicine” Microencapsulation helps protect and track therapeutic cells, showing promise for treating various diseases, but more work is needed to improve the technology.
25 citations,
December 2001 in “Expert Opinion on Pharmacotherapy” Potassium channel openers show promise for treating heart disease and other conditions, but more research is needed to fully understand their effects and safety.
165 citations,
September 2001 in “Genes & development” CDP is crucial for lung and hair follicle cell development.
10 citations,
January 2014 in “Endocrinology & metabolic syndrome” PCOS is a long-term condition that needs more research for better understanding and treatment.
77 citations,
May 2012 in “Expert Opinion on Emerging Drugs” New treatments for male hypogonadism are effective and should be personalized.
2 citations,
October 2015 in “Primary Care: Clinics in Office Practice” Doctors should diagnose hair loss by examining the patient and possibly doing tests, and then treat it based on the type, which may prevent permanent hair loss.
37 citations,
May 1999 in “Australasian Journal of Dermatology” Early diagnosis and treatment are crucial for preventing permanent hair loss in various scalp conditions, and while new treatments are promising, more research is needed to evaluate their effectiveness.
October 2023 in “IntechOpen eBooks” Genes and epigenetic changes are important in the development of Polycystic Ovary Syndrome.
14 citations,
April 2021 in “Biology” Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.
9 citations,
July 2021 in “Frontiers in Pharmacology” Cholesterol-modified siRNAs targeting certain genes increased hair growth in mice.
2 citations,
September 2022 in “Frontiers in Immunology” T-regulatory cells are important for skin health and can affect hair growth and reduce skin inflammation.
18 citations,
March 2020 in “Frontiers in Neuroendocrinology” The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.
19 citations,
December 2016 in “The journal of pharmacology and experimental therapeutics/The Journal of pharmacology and experimental therapeutics” Certain drugs increase calcium levels in cancer cells by triggering internal calcium release.
L-PGDS has specific binding sites for its functions and could help in drug delivery system design.
75 citations,
October 2016 in “Genes & Development” Cells in hair follicles help create fat cells in the skin by releasing a protein called Sonic Hedgehog.
December 2020 in “Current Sexual Health Reports” Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.
20 citations,
September 2015 in “Pediatric Annals” PCOS in teen girls should be managed with lifestyle changes and sometimes medication to improve symptoms and health.
November 2023 in “Frontiers in Neuroendocrinology” Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.