Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study observed that a self-emulsifying drug delivery system for finasteride significantly enhanced bioavailability in rats compared to commercial tablets, but the formulation was found to be thermodynamically unstable.

In this study using a mouse model, the authors reported that the synthetic antioxidant TS-13 effectively inhibited tumor growth comparably to doxorubicin and reduced chemotherapy side effects, such as weight loss, splenotoxicity, and alopecia, more effectively when combined with the cytostatic treatment.

This study found that the type of reporter significantly influences the detection of cancer therapy-induced alopecia signals, highlighting differences in signal amplification between patients and healthcare professionals.

This study analyzed data from the FDA Adverse Event Reporting System to evaluate cancer therapy–induced alopecia, finding that reporter type significantly affects signal detection, with docetaxel showing the highest disproportionate association overall, and vismodegib ranking highest among healthcare professional reports.

This review summarizes recent advances in alopecia management, focusing on combining synthetic and herbal therapies with innovative drug delivery systems like nanocarriers to enhance effectiveness and reduce side effects, while noting challenges with skin penetration and bioavailability.

This study identified known and potential novel adverse events, such as squamous cell carcinoma and dehydration, for vismodegib, underlining the importance of monitoring especially in the first two months of treatment.

This review highlights the potential of self-powered nanogenerators in revolutionizing biomedical devices by using biomechanical or environmental energy, focusing on applications like regenerative hair growth, drug release patches, and electronic skin while evaluating challenges such as energy efficiency and biocompatibility.

This review paper highlights the development and application of organic and biogenic nanocarriers for delivering bioactives, focusing on eco-friendly and sustainable nanotechnology strategies while addressing challenges like toxicity and paving the way for future innovations in green solution approaches.

This review discusses therapeutic deep eutectic solvents as promising "green" solutions for enhancing drug solubility and delivery through the skin, reporting no new clinical results and highlighting future research directions.

This review discusses the transmission and immune response of SARS-CoV-2 and highlights ongoing research for developing vaccines and antiviral treatments, but it presents no new clinical findings.

This review summarizes the composition, bioactive functions, and potential industrial applications of rice bran polysaccharides, focusing on how extraction methods and modifications impact their biological activities.

This review highlights brimonidine’s potential as a dermatological agent, noting its ability to improve rosacea-related facial redness and its effectiveness in various other skin conditions due to its vasoconstrictive and anti-inflammatory actions, with minimal systemic absorption and a favorable safety profile for long-term use.

This review discusses the mechanisms of laser and IPL hair removal, particularly for darker skin types, and reports no new findings, highlighting potential adverse effects like pigmentation changes or scarring with improper use.

This study suggests that follicular unit viability during hair transplantation is best preserved at lower storage temperatures, specifically around 4 °C, and provides insights into optimal cooling practices to enhance transplant success.

This article reviews the use of light-based technologies for hair removal, detailing different laser systems and treatment protocols, but reports no new clinical results.

This literature review reported that scalp hypothermia significantly decreases the occurrence of chemotherapy-induced alopecia, increasing effectiveness by 2.7-fold in controlled clinical trials and 3.9-fold in randomized trials, and highlighted a need for standard guidelines for its use.

This study reviewed treatments for chemotherapy-induced hair loss, finding that scalp cooling is FDA-approved for prevention, while minoxidil and bimatoprost may aid post-chemotherapy regrowth. The authors emphasized tailored therapies and the potential utility of tools like trichoscopy and trichogram.

This article reviews the pathophysiology of chemotherapy-induced alopecia and reports that scalp cooling can reduce hair loss by 50% in patients with early breast cancer receiving chemotherapy, without compromising survival or increasing scalp metastasis risk.

This review explores the use of topical and transdermal delivery for drugs and cosmetics, highlighting the benefits of avoiding side effects and rapid metabolism, with a focus on nanoparticulate formulations and techniques for studying skin penetration.

In this review, researchers introduced clinically tunable siRNA delivery systems for hair loss treatment, discussing design principles and analyzing relevant clinical trials to propose a framework for optimizing siRNA delivery in a clinical context.

This review discusses the significant progress in the diagnosis and treatment of hair loss disorders over the last 30 years and reports no new clinical results.

This review outlines the role of mechanical forces in the development of sensory organs like eyes and ears, emphasizing insights from recent animal studies and microfabricated organoid systems; it presents no new experimental results.

This article provides a narrative on managing dermatologic side effects from cancer therapies and suggests strategies that oncologists could adopt, but it reports no new clinical findings.

This article describes the significance of the Italian Association of Plastic Aesthetic Surgery's annual congress in European aesthetic plastic surgery, but reports no new research findings.

This paper reviews various causes of alopecia in cancer patients and highlights the importance of understanding these mechanisms for effective management, but reports no new findings.

This review highlights the challenges and management strategies associated with persistent chemotherapy-induced alopecia, detailing the psychosocial impacts, follicular pathobiology, and available treatments such as scalp cooling and minoxidil, ultimately proposing a clinical algorithm to transform it into a preventable and manageable condition.

This study reviewed existing methods to prevent chemotherapy-induced hair loss, highlighting FDA-approved scalp cooling as currently the most effective yet still insufficient solution and noting the need for more reliable treatments to better support cancer patients.

This review discusses the common occurrence of docetaxel-induced hair loss in cancer patients, including permanent cases, and highlights current and experimental strategies like scalp cooling, minoxidil, and new clinical trials for managing and preventing this side effect.

This article reviews current approaches to managing anagen effluvium, emphasizing patient education and strategies that can promote hair regrowth and reduce psychological distress, but reports no new research results.