June 2025 in “Clinical and Experimental Dermatology” In this case report, a 25-year-old woman with alopecia areata experienced hair regrowth after treatment with baricitinib, despite not responding to conventional treatments, with the new hair initially appearing dark brown.
May 2025 in “Skin Appendage Disorders” This review reports that psoriatic alopecia, a type of hair loss linked to psoriasis, is difficult to diagnose and often resistant to conventional treatments, highlighting the need for further research into its immune-related mechanisms and personalized treatment approaches for better management.
May 2025 in “Biomedicine & Pharmacotherapy” This study found that HPD is a potent activator of hair follicle regeneration, surpassing the efficacy of conventional minoxidil treatment by modulating Wnt/β-catenin signaling and enhancing follicular proliferation, indicating its potential as a non-invasive hair restoration therapy.
In this case study, gentian violet in diluted shampoo successfully alleviated symptoms of a Malassezia pachydermatis infection in a cat initially unresponsive to conventional treatments.
April 2025 in “Journal of Cosmetic and Laser Therapy” This study found that QR678 Neo® significantly enhanced hair regrowth, density, and shaft diameter in males with advanced androgenetic alopecia undergoing hair transplant surgery, compared to a conventional method, making it a promising adjunct treatment option.
April 2025 in “International Journal of Homoeopathic Sciences” In this case study, individualized classical homeopathy was reported to effectively promote significant hair regrowth and improve emotional stability in a patient with alopecia areata, showcasing a potential holistic and sustainable alternative to conventional treatments.
March 2025 in “Journal of Environmental Science and Engineering B” This study analyzed soil, water, and carrot samples in Vietnam, and found that organic farming can reduce heavy metal levels in carrots compared to conventional methods, potentially improving their nutritional safety.
January 2025 in “International Journal of Homoeopathic Sciences” This article discusses individualized homeopathy for treating alopecia areata and reports promising results, suggesting potential effectiveness; however, it highlights the unpredictability of hair follicle remission with conventional treatments.
January 2025 in “International Journal of Research in Medical Science” The researchers reported that treating Alopecia Areata patients with the homeopathic remedy Fluoric Acid resulted in substantial hair regrowth and reduced relapse rates over a 6-year period, suggesting it may be an effective alternative to conventional treatments.
January 2025 in “中医药研究与应用(Research and application of traditional Chinese medicine)” In this study involving acne patients, researchers compared the effects of combined fire needle and salicylic acid therapy with conventional treatment, measuring improvements in skin lesion severity, skin barrier function, and microbiota diversity; results are not reported in the abstract.
This study focused on developing a nanoemulsion-based gel for delivering minoxidil, aiming to enhance its contact time with the scalp and potentially improve skin absorption compared to conventional topical solutions.
December 2024 in “Asian Journal of Pharmaceutical and Clinical Research” This study found that the combination of platelet-rich plasma with topical minoxidil and finasteride was more effective in treating androgenetic alopecia than the conventional minoxidil and finasteride therapy alone.
November 2024 in “Research Journal of Pharmacognosy and Phytochemistry” This study developed an herbal shampoo using beetroot and sunflower seed extracts, aiming to provide multiple hair benefits compared to conventional shampoos, which typically offer only a single benefit for hair and scalp care.
November 2024 in “International Journal of Applied Pharmaceutics” This study found that a fenugreek seed extract nanoformulation significantly improved hair growth and length in Wistar rats with alopecia, outperforming conventional gels and oils, suggesting enhanced skin penetration and reduced side effects.
November 2024 in “Skin Appendage Disorders” This study reported that online misinformation about alopecia is widespread, with myths including incorrect causes, criticism of conventional treatments, and promotion of unproven "natural" remedies, which could negatively affect patient outcomes.
October 2024 in “American Journal of Case Reports” This case report describes a 54-year-old Saudi woman with systemic lupus erythematosus and severe alopecia, where conventional treatments were ineffective. When belimumab was ineffective, baricitinib led to significant improvement in her condition, suggesting further research is needed to evaluate baricitinib's role in managing SLE.
August 2024 in “World Journal of Biology Pharmacy and Health Sciences” In this case, ayurvedic medicines were reported to effectively manage a patient with alopecia areata, with fewer side effects and reduced relapse rates compared to conventional treatments.
August 2024 in “Journal of Controlled Release” In a study using an AGA mouse model, researchers observed that a novel topical gel combining hybrid extracellular vesicles, gold nanoparticles, and finasteride accelerated hair regrowth and improved hair quality more effectively than conventional minoxidil treatment, presenting a promising option with fewer side effects.
August 2024 in “Clinical Cosmetic and Investigational Dermatology” In this case report, a patient with severe erythrodermic psoriasis and diffuse alopecia who was unresponsive to conventional treatments showed complete resolution of skin lesions and alopecia after being treated with ixekizumab.
July 2024 in “Anti-Infective Agents” This study explored the development of a herbal anti-dandruff shampoo using natural polyherbal tincture and reported strong antimicrobial effects, which suggests it may be a safer and more effective alternative to conventional solutions that can cause side effects like hair loss and irritation.
July 2024 in “Minerva Digital Library (Universidad EAN)” In this study, the researchers addressed the development of a new hair treatment prototype as an innovative alternative to current chemical hair straightening products, highlighting possible health risks and environmental concerns associated with conventional treatments. Results are not provided in the abstract.
July 2024 in “Pharmaceutics” In a mouse model of androgenetic alopecia, this study found that a novel hydrogel containing minoxidil-incorporated engineered exosomes (Gel@MNs) enhanced hair regeneration more effectively than conventional minoxidil, increasing hair follicle number and size while reducing skin irritation.
June 2024 in “International Research Journal of Modernization in Engineering Technology and Science” This study developed and evaluated a Neem, Tulsi, and Aloe vera-based anti-dandruff shampoo, finding it effective and safe, potentially offering a natural alternative to conventional antifungal shampoos for managing dandruff and maintaining scalp health.
June 2024 in “British Journal of Dermatology” In this study, researchers analyzed internet and social media content related to hair loss, finding widespread misinformation about its causes and treatments, including unfounded criticisms of conventional therapies and promotion of alternative remedies.
June 2024 in “ACTA SCIENTIAE VETERINARIAE” This study reported a case of equine ringworm infection in a 2-year-old horse caused by Nannizzia gypsea, confirmed through culture and SYBR-Green real-time PCR techniques, demonstrating that qPCR allows specific detection of dermatophytes more rapidly than conventional methods.
May 2024 in “JEADV Clinical Practice” In this study, researchers found that among patients with severe alopecia areata, a change in SALT scores of 42 or 43 points represents meaningful improvement, highlighting the need to consider individual treatment goals beyond conventional low SALT score targets when assessing treatment benefits.
April 2024 in “International Research Journal of Ayurveda & Yoga” This study explored Ayurvedic principles for skin care and reported that these traditional practices offer safe, affordable, and effective solutions for various dermatological issues, providing promising alternatives to conventional cosmetics.
In this case report, off-label onabotulinumtoxin-A was successfully used to treat trichodynia, a painful scalp sensation associated with hair loss, in a patient unresponsive to conventional therapies.
March 2024 in “Deleted Journal” This review highlights various medicinal plants, such as Saraca asoka and Moringa olifera, which have shown potential activity in treating polycystic ovarian syndrome, offering a complementary approach alongside conventional treatments due to concerns over their long-term side effects and limited effectiveness.
January 2024 in “International Journal of Homoeopathic Sciences” In this case study, a 29-year-old woman's acne scars improved alongside enhancements in emotional well-being following six months of personalized homeopathic treatment, suggesting potential benefits for individuals unresponsive to conventional therapies, though further research is needed to substantiate these findings.