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April 2022 in “Rheumatology” This case study describes a 4-year-old boy with juvenile dermatomyositis whose severe subcutaneous edema resisted conventional treatment, necessitating aggressive immunosuppression for disease control.
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June 2016 in “Annals of the rheumatic diseases” In this study, researchers found that retinoids might improve lupus nephritis resistant to conventional treatments, but the sample size was too small for significant results, and side effects were noted.
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September 2004 in “Physica D: Nonlinear Phenomena” This study developed a new method for analyzing multivariate time-series data that successfully predicts website competition dynamics and outperforms conventional methods in identifying and predicting competitive structures.
This study utilized a pigmented human epidermal equivalent model to incorporate melanocytes into the epidermis and found enhanced differentiation potential compared to conventional in vitro systems, reflecting in vivo cellular trajectories and highlighting melanocyte-to-keratinocyte communication pathways.
August 2026 in “International Journal of Allied Medical Sciences and Clinical Research” This review highlights that herbal shampoos containing ingredients like custard apple leaves and aloe vera offer a natural and safe alternative to conventional chemical-based shampoos, effectively cleansing the scalp and supporting healthy hair without harsh chemicals, according to this source.
July 2026 in “Frontiers in Bioengineering and Biotechnology” This study reports that Echinacea-loaded silk fibroin/chitosan dressings may effectively promote scarless skin regeneration and accelerate wound healing compared to conventional treatments.
July 2026 in “International Journal of Homoeopathic Sciences” In this report from Dr Batra's Homeopathy Clinic, a 21-year-old female with Female Pattern Hair Loss experienced notable improvement in hair fall, scalp health, and overall well-being after receiving individualized homeopathic treatment over twelve months, despite limited success with previous conventional therapies.
June 2026 in “Journal of General-Procedural Dermatology & Venereology Indonesia” This study concluded that oral tofacitinib significantly improved symptoms in patients with lichen planus pigmentosus who did not respond to conventional treatments, showing it as a viable alternative.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review critically evaluated natural hair growth actives for the 2025–2026 marketplace and found they show potential as alternatives to conventional therapies for androgenetic alopecia, with favorable safety and patient acceptance, though challenges such as formulation instability and limited follicular penetration remain.
February 2026 in “International Journal of Advanced Research in Science Communication and Technology” In this review, researchers explored the potential of herbal shampoos as effective and safe alternatives to conventional anti-dandruff treatments, highlighting that polyherbal formulations may offer comparable or superior benefits with fewer side effects.
This study found that plasma-activated water significantly improved wound healing in diabetic rats compared to both atmospheric pressure cold plasma and conventional dressings.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This review highlights the growing popularity and benefits of herbal shampoos, which use plant-based extracts to provide a gentle, effective, and environmentally friendly alternative to conventional chemical shampoos, promoting hair health and eco-sustainability.
October 2025 in “International Journal of Research and Review” This study highlights the potential benefits of herbal soaps and shampoo bars as eco-friendly alternatives to conventional cosmetics, noting their antibacterial, antifungal, and antioxidant properties as well as sustainability advantages such as reduced plastic use and avoidance of synthetic chemicals.
July 2025 in “Chinese Journal of Dermatology” This study concluded that the effectiveness and safety of a domestic follicular extraction system were similar to conventional follicular unit excision in patients undergoing hair transplant surgery for androgenetic alopecia.
July 2025 in “International Journal of Pharmacognosy and Pharmaceutical Sciences” This review discusses acne's common triggers, challenges with conventional treatments, and the potential of alternative therapies to reduce side effects and enhance outcomes, highlighting an increasing interest in safer approaches due to the limitations of current topical options.
April 2025 in “International Journal of Cosmetic Science” This study found that using 1,4-butylenediamine bismaleimide for hair perming through thiol-Michael click chemistry offers comparable efficiency to conventional oxidative methods, with enhanced durability and reduced damage to hair fibres, preserving mechanical, color, and surface properties.
February 2025 in “PubMed” This article discusses the need for rigorous trials to compare the effectiveness and safety of CAM supplements with conventional dermatologic therapies, reporting no new findings.
January 2025 in “International Journal of Biological Innovations” This review article discusses the potential benefits of phytochemicals in hair care, highlighting their ability to improve scalp health, reduce dandruff, and promote hair growth, while emphasizing their safety and minimal side effects compared to conventional therapies.
December 2024 in “Current Cosmetic Science” This review introduces Ayurvedic remedies as a promising natural treatment for premature greying of hair, highlighting the use of Vedic plant taxonomy to accurately identify herbs that stimulate melanogenesis and restore hair pigmentation, offering a safer alternative to conventional chemical treatments.
September 2024 in “Skin Appendage Disorders” This case report describes a 21-year-old woman with circumscribed alopecia areata incognita, who experienced a sustained positive response to treatment with oral tofacitinib after conventional treatments frequently failed to provide lasting effects.
April 2024 in “Journal of biomedical and pharmaceutical research” This study highlights the promise of nanoparticles in cancer treatment, addressing limitations of conventional chemotherapy such as drug resistance and toxicity, by using nanocarriers like gold nanoparticles and dendrimers to improve drug delivery.
March 2024 in “Clinical, cosmetic and investigational dermatology” This study reported that five patients with alopecia areata achieved satisfactory results using 15 mg of Upadacitinib daily after conventional treatments had failed, without experiencing adverse events.
February 2024 in “Journal of ayurveda and integrated medical sciences” This case study suggests that Ayurvedic treatment, including Karanj oil, herbal churna, and leech therapy, provided significant hair regrowth in a 16-year-old with alopecia areata after three months, despite previous unsuccessful conventional medicine treatments.
December 2023 in “Journal of Asia Pacific Aesthetic Sciences” This review discusses the potential of bone marrow mesenchymal stem cell-derived cytokines and growth factors as a promising alternative to conventional treatments for androgenetic alopecia, given their favourable outcomes in hair regrowth and follicle repair.
October 2023 in “Al-Anbar medical journal” This study found that a new clinic-based modified hair fall count method is a valid tool for assessing hair loss in women, showing strong association and high precision compared to the conventional home-based method.
July 2018 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that finasteride delivered through a nano-transferosomal gel showed improved penetration through skin layers compared to a conventional gel, suggesting a potential alternative for oral administration.
January 2017 in “Clinical approaches and procedures in cosmetic dermatology” This review explores clinical studies on low-level laser therapy (LLLT) for alopecia and suggests it may benefit patients unresponsive to conventional treatments, but larger studies are needed to confirm efficacy.
July 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” This study concluded that a new model of reconstructed human epidermis using keratinocytes from plucked hair follicles offers a less-invasive alternative to conventional skin-derived models for skin research.
March 2016 in “Indian Journal Of Applied Research” This report presents a case of refractory thyrotoxicosis where the patient required a total thyroidectomy after resistance to conventional treatments including antithyroid drugs and radioactive iodine.
December 2016 in “Journal of Dermatology and Dermatologic Surgery” In this study, the Instant Follicular Hair Unit Transplant technique demonstrated superior hair growth compared to conventional FUE in patients with androgenetic alopecia, although it requires a steeper learning curve for surgeons.