Management of Severe Childhood Hypertension with Minoxidil: A Controlled Clinical Study

July 1977 in “ The Journal of Pediatrics ”

Alan R. Sinaiko, Bernard L. Mirkin

TLDR Minoxidil helps lower blood pressure in kids with severe hypertension, but may cause temporary excessive hair growth.

The study evaluated the effectiveness of different antihypertensive regimens in children with severe hypertension and found that minoxidil, in combination with propranolol and hydrochlorothiazide, was effective in reducing blood pressure. The only side effect observed was hypertrichosis, or excessive hair growth, which was not permanent. The study suggests that minoxidil may be a beneficial addition to current antihypertensive therapy for severe hypertension in children.

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Research cited in this study

3 / 3 results

research Long-Term Treatment of Severe Hypertension with Minoxidil, Propranolol, and Furosemide

55 citations , October 1975 in “Circulation”

Minoxidil, propranolol, and furosemide effectively control severe hypertension, but may cause sodium retention.

research Minoxidil in Severe Hypertension: Value When Conventional Drugs Have Failed

50 citations , September 1975 in “American Heart Journal”

Minoxidil effectively controls blood pressure in severe cases, but may cause fluid retention and edema.

$Minoxidil: An Alternative to Nephrectomy for Refractory Hypertension$

research Minoxidil: An Alternative to Nephrectomy for Refractory Hypertension

180 citations , July 1973 in “The New England Journal of Medicine”

Minoxidil effectively lowers blood pressure with few side effects.

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community Minoxidil seems logistically impossible and impractical to use

in Minoxidil 136 upvotes 2 years ago

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community 6 week update fellas, 5mg oral minoxidil. Pics are 2nd June – 10th July

in Progress Pictures 3 years ago

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community Topical minoxidil brand (and form of application) matters. You can be a hyper-responder to one product and a non-responder to another.

in Minoxidil 18 upvotes 8 months ago

Different minoxidil formulations affect hair growth and side effects. Higher propylene glycol and pH levels improve effectiveness but can cause scalp irritation.

community Minoxidil 3 Months Crazy Transformation?

in Is this regrowth? 580 upvotes 7 months ago

A user experienced significant hair regrowth using topical minoxidil, water-soluble pumpkin seed oil, and saw palmetto. Despite not using finasteride, the user reported reduced hair loss and increased hair growth, especially around the temples and beard.

community What's "wrong" with oral minoxidil, exactly?

in Minoxidil 173 upvotes 1 year ago

Oral minoxidil can boost hair growth but may cause side effects like heart palpitations and increased body hair. Many prefer topical minoxidil due to fewer side effects.

community Topical Minoxidil is a pain in the ass for diffuse thinners

in Minoxidil 95 upvotes 2 years ago

Topical minoxidil being a difficult product to apply, with users considering finasteride, RU58841, and oral minoxidil as alternative treatments for diffuse thinning hair. Other advice includes shaving the head in the first 3 months of using minoxidil and finding ways to apply it without saturating the hair.

Related Research

1 / 1 results

research Management of Severe Childhood Hypertension with Minoxidil: A Controlled Clinical Study

36 citations , July 1977 in “The Journal of Pediatrics”

Minoxidil helps lower blood pressure in kids with severe hypertension, but may cause temporary excessive hair growth.