Management of Severe Childhood Hypertension with Minoxidil: A Controlled Clinical Study

July 1977 in “ The Journal of Pediatrics ”

Alan R. Sinaiko, Bernard L. Mirkin

TLDR Minoxidil helps lower blood pressure in kids with severe hypertension, but may cause temporary excessive hair growth.

The study evaluated the effectiveness of different antihypertensive regimens in children with severe hypertension and found that minoxidil, in combination with propranolol and hydrochlorothiazide, was effective in reducing blood pressure. The only side effect observed was hypertrichosis, or excessive hair growth, which was not permanent. The study suggests that minoxidil may be a beneficial addition to current antihypertensive therapy for severe hypertension in children.

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Research cited in this study

3 / 3 results

research Long-Term Treatment of Severe Hypertension with Minoxidil, Propranolol, and Furosemide

55 citations, October 1975 in “Circulation”

Minoxidil, propranolol, and furosemide effectively control severe hypertension, but may cause sodium retention.

research Minoxidil in Severe Hypertension: Value When Conventional Drugs Have Failed

50 citations, September 1975 in “American Heart Journal”

Minoxidil effectively controls blood pressure in severe cases, but may cause fluid retention and edema.

$Minoxidil: An Alternative to Nephrectomy for Refractory Hypertension$

research Minoxidil: An Alternative to Nephrectomy for Refractory Hypertension

180 citations, July 1973 in “The New England Journal of Medicine”

Minoxidil effectively lowers blood pressure with few side effects.

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Related Research

1 / 1 results

research Management of Severe Childhood Hypertension with Minoxidil: A Controlled Clinical Study

36 citations, July 1977 in “The Journal of Pediatrics”

Minoxidil helps lower blood pressure in kids with severe hypertension, but may cause temporary excessive hair growth.