research Inhibition of JAK-STAT Signaling with Baricitinib Reduces Inflammation and Improves Cellular Homeostasis in Progeria Cells
Baricitinib reduces inflammation and improves cell health in premature aging cells.
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540-570 / 763 resultsresearch Disturbed Epidermal Structure in Mice with Temporally Controlled Fatp4 Deficiency
Fatp4 is crucial for healthy skin development and function.
research Biallelic Variants in Lanosterol Synthase (LSS) Cause Palmoplantar Keratoderma-Congenital Alopecia Syndrome Type 2
Certain genetic changes in the LSS gene cause a rare skin and hair condition.
research Animals in Dermatology
Using animal names for skin conditions helps with learning and memory.
research Novel Splicing-Site Mutation in DCAF17 Gene Causing Woodhouse-Sakati Syndrome in a Large Consanguineous Family
A new mutation in the DCAF17 gene was found to cause Woodhouse-Sakati syndrome in a large family.
research Novel Association of Trichothiodystrophy With Autoimmune Thyroiditis and Autoimmune Hemolytic Anemia: A Case Report
A child with trichothiodystrophy also had autoimmune thyroiditis and anemia, which is a new finding.
research Trichothiodystrophy Hair Shafts Display Distinct Ultrastructural Features
Trichothiodystrophy hair is structurally abnormal with protein and organization issues.
research Mechanical Forces Across Compartments Coordinate Cell Shape and Fate Transitions to Generate Tissue Architecture
Mechanical forces are crucial for shaping cells and forming tissues during development.
research Single-Cell RNA Sequencing of Different Fibroblast Populations Cultured from Female Scalp Reveals Significant Alterations to Transcriptional Profiles with Age
Aging changes female scalp cells, likely affecting hair health.
research Novel Insights Into Cardiocutaneous Syndromes
Understanding genetics is crucial for treating heart and skin diseases.
research Synergism Between Tocotrienol and Injectable Platelet-Rich Fibrin in Hair Follicle Stem Cells Proliferation: An In Vitro Study
Aloe Vera and injectable platelet-rich fibrin (i-PRF) together can speed up and improve hair growth when used in the right amounts.
research Modulation of the 6-Position of Benzopyran Derivatives and Inhibitory Effects on the Insulin Releasing Process
Changing the 6-position on benzopyran molecules affects insulin release, with some compounds showing strong inhibitory effects.
research Minoxidil-Induced Cardiac Hypertrophy in Guinea Pigs
Minoxidil may cause heart issues in guinea pigs, suggesting potential harm for users with heart conditions.
research Pharmacology and Pharmacokinetics of Minoxidil
Minoxidil treats high blood pressure and side effects can be managed.
research Incomplete Recovery of Erectile Function in Rats After Discontinuation of Dual 5-Alpha Reductase Inhibitor Therapy
Rats had lasting erectile problems after stopping a certain medication.
research Evidence of Increased DNA Methylation of the Androgen Receptor Gene in Occipital Hair Follicles from Men with Androgenetic Alopecia
Men with hair loss have more DNA changes in back-of-head hair follicles, possibly protecting them from thinning.
research Influence of the Alkylsulfonylamino Substituent Located at the 6-Position of 2,2-Dimethylchromans Structurally Related to Cromakalim: From Potassium Channel Openers to Calcium Entry Blockers?
New compounds similar to cromakalim were less effective at inhibiting insulin release but improved in solubility and one acted as a calcium entry blocker, not a potassium channel opener.
research Prescribing to Save Patients Money: Ethical Considerations
Doctors should prescribe cheaper, off-label medication and teach patients how to use it to save money ethically.
research Investigating the Relationship Between the Hair Fiber Proteome and Hair Quality
Hair quality is genetically determined and linked to its composition and strength.
research 5-Alpha-Reductase Inhibitors for Lower Urinary Tract Symptoms Secondary to Benign Prostatic Obstruction
5-alpha-reductase inhibitors help treat urinary symptoms from an enlarged prostate.
research Stem Cells Sheltered from Air-Raids Repair Airways
Myoepithelial cells can repair airways after severe injury.
research MicroRNA Control of Signal Transduction
MicroRNAs are crucial in controlling cell signaling, affecting cancer and tissue regeneration.
research Cultured Peribulbar Dermal Sheath Cells Can Induce Hair Follicle Development and Contribute to the Dermal Sheath and Dermal Papilla
Certain cells from hair follicles can create new hair and contribute to hair growth when implanted in mice.
research ATP-Dependent Chromatin Remodeling During Mammalian Development
ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.
research What Does the Concept of the Stem Cell Niche Really Mean Today?
Stem cell niches support, regulate, and coordinate stem cell functions.
research Dermal Adipocyte Lipolysis and Myofibroblast Conversion Are Required for Efficient Skin Repair
Fat cells in the skin help start healing and form important repair cells after injury.
research Potassium Channel Therapeutics at the Bedside
Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.
research Potassium Channel Openers: Pharmacological and Clinical Aspects
Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.
research Protection Against Chemotherapy-Induced Alopecia
No treatment fully prevents hair loss from chemotherapy yet.
research Dermal White Adipose Tissue: A New Component of the Thermogenic Response
Skin fat helps with body temperature control and has other active roles in health.