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Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

Enzymes called PADIs play a key role in hair growth and loss.

Surgery to fix a broken upper arm bone can sometimes lead to nerve damage.

People with cleft lip and palate often have respiratory problems.

Passiflora incarnata may help with anxiety and sleep issues but has side effects; teleconsultation for heart failure can improve quality of life; increased screen time for children during the pandemic led to more clinical complaints; older and severely affected COVID-19 patients are more likely to have long-term symptoms.

Passiflora incarnata may help with anxiety but has risks and drug interactions. There's a genetic link between Fragile X Syndrome and Autism Spectrum Disorder. 6.7% of urine cultures showed hospital-acquired urinary tract infections. Children used screens more during COVID-19, causing various health complaints. Autism Spectrum Disorder is often underdiagnosed in females. Dissociative disorders in childhood sexual abuse victims are more common in males. Most pregnant teenagers are not dissatisfied with their body image but worry about weight. Diagnosing tuberculosis after knee surgery is challenging due to non-specific symptoms. Post-COVID-19 syndrome is more common in older, severely affected patients. Psychiatrists should be part of pain management teams due to the psychological aspects of pain.

Different immune cells like platelets, mast cells, neutrophils, macrophages, T cells, B cells, and innate lymphoid cells all play roles in skin wound healing, but more research is needed due to inconsistent results and the complex nature of the immune response.

Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Chicken feather gene mutation helps understand human hair disorders.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

Skin lymphatic vessels are essential for hair growth.

Four new substances—minoxidil, ferrimanitol ovalbumin, clarithromycin, and glucosamine-hydrochloride—can cause occupational asthma.

Transnasal cooling could reveal new insights into various physiological conditions and may be a natural way to transfer heat from the brain.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.

Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.

Adult stem cells are important for tissue repair and have therapeutic potential, but more research is needed to fully use them.

Genetic variations affect dutasteride treatment response for male pattern hair loss.

Skin stem cells remember past inflammation, helping them respond better to future injuries and possibly aiding in treating skin issues.

YAP and TAZ are crucial for skin cell growth and repair.

Some small molecule antivirals show promise against COVID-19, but more research is needed to understand and improve them.

IL-1 family cytokines are crucial for skin defense and healing, but their imbalance can cause skin diseases.

Foxp3+ Regulatory T Cells are important for immunity and tolerance, affect hair growth and wound healing, and their dysfunction can contribute to obesity-related diseases and other health issues.

The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.

Neurotoxins can affect neurotransmitter release and have potential in treating muscle, pain, and cancer conditions, but more research is needed on how they work.

Type 3 Innate Lymphoid Cells help maintain skin health and balance, and are involved in skin diseases and healing.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

The document concludes that inherited epidermolysis bullosa is a challenging genetic condition requiring multidisciplinary care and new treatments.

Children's screen time increased during the pandemic, causing various health issues.